38778-79-9Relevant articles and documents
Synthesis and structure-activity relationships of 9-substituted acridines as endothelin-A receptor antagonists
Cheng,Lee,Klutchko,Winters,Reynolds,Welch,Flynn,Doherty
, p. 2999 - 3002 (1996)
Screening of a compound library against endothelin receptors (ET(A) and ET(B)) revealed PD 102566 (compound 1) as an ET(A) selective antagonist. Synthesis and structure-activity relationships (SAR) of a series of analogs are described.
A simple and fast synthetic pathway of β-Enamino-esters by condensation of β-Keto ester with aliphatic and aromatic amines in ethanol
Kouadri,Ouahrani,Missaoui,Chebrouk,Gherraf
, p. 2575 - 2578 (2015/12/11)
The β-keto ester undergoes condensation reactions with aliphatic and aromatic amines in ethanol to give high-yielding β-enamino ester. The method is simple, cost-effective and environmentally benign. Structural characterization of the synthesized compound
General, mild and efficient synthesis of β-enaminones catalyzed by ceric ammonium nitrate
Sridharan, Vellaisamy,Avenda?o, Carmen,Menéndez
, p. 881 - 884 (2008/02/02)
Ceric ammonium nitrate catalyzes the reaction between aromatic or aliphatic primary amines and a variety of β-dicarbonyl compounds, including β-ketoesters, β-ketothioesters and β-diketones. The reaction proceeds smoothly at room temperature in short react
