3881-28-5Relevant articles and documents
Structure-activity relationships of substituted 2,3,4,4a,5,10b-hexahydrobenz[h]isoquinoline-6(1H)-ones as 5-HT2C receptor antagonists
Stadler, Heinz,Wichmann, Juergen,Sleight, Andrew J.,Boes, Michael
, p. 669 - 671 (2007/10/03)
A series of cis and trans configured 2,3,4,4a,5,10b-hexahydro-benz[h]isoquinoline-6(1H)-ones 2 were studied with respect to the binding affinity to the 5-HT2 subtype receptors. The influence of substituents in positions 7 (R1), 8 (R
Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines
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, (2008/06/13)
Novel 4-aryloxy- and 4-arylthio-3-phenylpiperidines and related compounds, physiologically acceptable salts thereof and intermediates therefor possessing analgesic, antidepressant properties, and a process for the preparation of such compounds, derivatives and intermediates are described.