38841-54-2

Basic information

• Product Name: 2,6-DICHLORO-4-METHYLNICOTINAMIDE
• Synonyms: 2,6-DICHLORO-4-METHYL-3-PYRIDINECARBOXAMIDE;2,6-DICHLORO-4-METHYLNICOTINAMIDE;NSC 341976;3-PyridinecarboxaMide, 2,6-dichloro-4-Methyl-
• CAS NO: 38841-54-2
• Molecular Formula: C7H6Cl2N2O
• Molecular Weight: 205.04
• Mol File: 38841-54-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 129-132/7mm
• Flash Point: 135.1°C
• Appearance: /
• Density: 1.448
• Vapor Pressure: 0.00117mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,6-DICHLORO-4-METHYLNICOTINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-4-METHYLNICOTINAMIDE(38841-54-2)
• EPA Substance Registry System: 2,6-DICHLORO-4-METHYLNICOTINAMIDE(38841-54-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 38841-54-2(Hazardous Substances Data)

Usage

General Description

2,6-Dichloro-4-methylnicotinamide is a chemical compound with the molecular formula C7H6Cl2N2O. It is a derivative of nicotinamide, an amide form of vitamin B3, and is commonly referred to as an analog of nicotinamide. 2,6-DICHLORO-4-METHYLNICOTINAMIDE is a white to off-white solid with a molecular weight of 203.04 g/mol. It is used in the synthesis of various pharmaceutical compounds and research purposes. 2,6-Dichloro-4-methylnicotinamide may have potential applications in the fields of medicine, pharmacology, and biochemistry due to its structural similarities to nicotinamide and its potential biological activities.

InChI:InChI=1/C7H6Cl2N2O/c1-3-2-4(8)11-6(9)5(3)7(10)12/h2H,1H3,(H2,10,12)

Upstream product

• 5444-02-0 2,6-dihydroxy-3-cyano-4-methylpyrimidine 
• 62774-90-7 2,6-dichloro-4-methyl-nicotinic acid 
• 56950-89-1 2,6-dichloro-4-methylnicotinoyl chloride 
• 5444-02-0 3-cyano-4-methyl-6-hydroxypyrid-2-one 
• 875-35-4 2,6-dichloro-4-methylnicotinonitrile 

Downstream Products

• 62774-90-7 2,6-dichloro-4-methyl-nicotinic acid 
• 1612761-99-5 benzoic acid 1-benzoyl-6-(3,5-dimethylpyrazol-1-yl)-4-methyl-1H-pyrazolo[3,4-b]pyridine-3-yl ester 
• 1612761-98-4 toluene-4-sulfonic acid 6-(3,5-dimethylpyrazol-1-yl)-4-methyl-1H-pyrazolo[3,4-b]pyridine-3-yl ester 
• 1612761-97-3 benzenesulfonic acid 6-(3,5-dimethylpyrazol-1-yl)-4-methyl-1H-pyrazolo[3,4-b]pyridine-3-yl ester 
• 129432-25-3 2,6-dichloro-3-amino-4-methylpyridine 

Relevant articles and documents

Synthesis and structure of novel 6-(pyrazol-1-yl)-4-methyl-1H-pyrazolo[3,4- b]pyridin-3-ol derivatives

New 6-(pyrazol-1-yl)pyrazolo[3,4-b]pyridin-3-ol compounds were synthesized by cyclization reaction from 2,6-dichloro-4-methylnicotinonitrile. Their derivatives exist as the 3-hydroxy tautomer. The structure of the compound 1a of one of the resulting compounds was studied in detail by X-ray diffraction.

OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.