3893-01-4

Basic information

• Product Name: 2,3-DIMETHOXYBENZYL CHLORIDE
• Synonyms: 2,3-DIMETHOXYBENZYL CHLORIDE;2,3-DIMETHOXYBENZYL CHLORIDE (50% IN METHYLENE CHLORIDE);1-(Chloromethyl)-2,3-dimethoxybenzene, alpha-Chloro-2,3-dimethoxytoluene
• CAS NO: 3893-01-4
• Molecular Formula: C₉H₁₁ClO₂
• Molecular Weight: 186.64
• Mol File: 3893-01-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 69-70.5℃
• Boiling Point: 95°C 1mm
• Flash Point: 89.3±18.4℃
• Appearance: /
• Density: 1.130±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.038mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: Keep Cold
• CAS DataBase Reference: 2,3-DIMETHOXYBENZYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHOXYBENZYL CHLORIDE(3893-01-4)
• EPA Substance Registry System: 2,3-DIMETHOXYBENZYL CHLORIDE(3893-01-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT, KEEP COLD, LACHRYMATOR
• Hazardous Substances Data: 3893-01-4(Hazardous Substances Data)

Usage

General Description

2,3-Dimethoxybenzyl Chloride, also known as the chemical formula C9H11ClO2, is a chemical compound that belongs to the class of organic compounds known as benzyl chlorides. It has aromatic and ether functionalities. The chemical is considered a relatively unstable and reactive compound and can undergo a series of significant chemical reactions maintained under controlled conditions. This chemical compound is primarily used in the field of organic synthesis as a reagent or intermediate. The exact mass of 2,3-Dimethoxybenzyl Chloride is 186.032028, and it has a monoisotopic mass of 186.032028 g/mol. It is crucial to handle and store this compound appropriately as due to its reactive characteristics it could result in unpredictable hazards. Its usual appearance is in the liquid form, light yellow to brown in color.

InChI:InChI=1/C9H11ClO2/c1-11-8-5-3-4-7(6-10)9(8)12-2/h3-5H,6H2,1-2H3

Upstream product

• 108-48-5 2,6-dimethylpyridine 
• 5653-67-8 2,3-dimethoxybenzyl alcohol 
• 86-51-1 2,3-dimethyoxybenzaldehyde 

Downstream Products

• 87664-47-9 2-(2,3-Dimethoxybenzyl)-pyrrol 
• 87664-48-0 3-(2,3-Dimethoxybenzyl)-pyrrol 
• 122849-97-2 (2,3-dimethoxybenzyl)triphenylphosphonium chloride 
• 75875-48-8 3,4-dihydro-6,7-dimethoxy-N-(2,3-dimethoxybenzyl)isoquinolinium chloride 
• 4468-57-9 2-(2,3-dimethoxyphenyl)acetonitrile 
• 1383792-23-1 C₂₀H₂₁NO₅ 
• 1147093-47-7 C₁₁H₁₇NO₂S 
• 125156-02-7 Methyl 4-(2,3-dimethoxybenzyl)-1-piperazinecarbodithioate 
• 3213-29-4 2,3-dimethoxyphenethylamine 
• 579-59-9 2,3-Dihydroxy-phenyl-ethylamin 
• 102606-91-7 1-acetoxymethyl-2,3-dimethoxy-benzene 
• 109937-92-0 1-(2,3-dimethoxy-benzyl)-5,6-dimethoxy-isoquinoline 
• 796074-04-9 (2,3-dimethoxy-phenyl)-acetic acid-(2,3-dimethoxy-phenethylamide) 
• 872788-11-9 1-(2,3-dimethoxy-benzyl)-5,6-dimethoxy-3,4-dihydro-isoquinoline 

Relevant articles and documents

PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES

[Problem] A problem is presented in that conventional photochromic compounds cannot be considered adequate in terms of the colorizing/decolorizing rate and durability, and the production process therefore has many steps. The present invention provides an industrially applicable photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability and can also be synthesized at a low cost. [Solution] This compound is characterized in that etheric oxygen atoms are bonded to the carbon atoms at position 1 of a pyranoquinazoline (8H-pyrano[3,2-f]quinazoline) skeleton and position 10 of a naphthopyran (3H-naphtho[2,1-b]pyran) skeleton, said compound having photochromic properties and being a photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability. Also provided is an industrially applicable photochromic compound that can be synthesized at a low cost.

5- substituted tetralones as inhibitors of ras farnesyl trransferase

The present invention provides novel 5-substituted tetralones of Formulas (I), (II), (III) and (IV) and pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, which are useful for treating and preventing uncontrolled or abnormal proliferation of tissues, such as cancer, atherosclerosis, restenosis, and psoriasis. Specifically, the present invention relates to compounds that inhibit the farnesyl transferase enzyme.

Synthesis of Substituted 1-Tetralones

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