389572-79-6Relevant articles and documents
cis-selective aziridination of cis- or trans-α,β-unsaturated amides using diaziridine
Hori, Kiyoto,Sugihara, Hiroyasu,Ito, Yoshio N.,Katsuki, Tsutomu
, p. 5207 - 5210 (1999)
Aziridination of αβ-unsaturated amides was effected by treatment with lithiated 3,3-pentamethylenediaziridine in high diastereoselectivity, cis- Aziridine was the predominant diastereomer irrespective of the geometry of the substrates. A stepwise mechanis
Highly diastereoselective aziridination of α,β-unsaturated amides using diaziridine
Ishihara, Hiroyuki,Ito, Yoshio N.,Katsuki, Tsutomu
, p. 984 - 985 (2007/10/03)
Racemic 3-cyclohexyl-1-methyldiaziridine was found to react with α,β-unsaturated amides in basic conditions, giving N-unprotected trans-aziridines, while 3,3-pentamethylenediaziridine had been reported to afford cis-aziridines in high diastereoselectivity