39087-48-4 Usage
Description
Calcium clofibrate is a calcium salt of clofibrate, a fibric acid derivative that functions as a lipid-regulating agent. It is utilized to decrease elevated serum cholesterol and triglyceride levels. As a fibrate medication, calcium clofibrate operates by enhancing the production of enzymes that break down triglycerides and by reducing the production of low-density lipoprotein (LDL) cholesterol. It is also thought to increase high-density lipoprotein (HDL) cholesterol levels, which can help in diminishing the risk of coronary artery disease. Despite its benefits, the use of calcium clofibrate has diminished due to the emergence of more potent and effective lipid-lowering agents. Moreover, it has been linked to adverse side effects such as gastrointestinal disturbances, and liver and muscle damage, which have further restricted its clinical application.
Uses
Used in Pharmaceutical Industry:
Calcium clofibrate is used as a lipid-regulating agent for the management of elevated serum cholesterol and triglyceride levels. It is employed to increase the production of enzymes that break down triglycerides and to reduce the production of LDL cholesterol, thereby potentially reducing the risk of coronary artery disease.
Used in Cardiovascular Health Management:
In the context of cardiovascular health, calcium clofibrate is used to increase HDL cholesterol levels, which is considered beneficial in reducing the risk of coronary artery disease. However, due to its side effects and the availability of alternative treatments, its use in this application has been limited.
Check Digit Verification of cas no
The CAS Registry Mumber 39087-48-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,8 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39087-48:
(7*3)+(6*9)+(5*0)+(4*8)+(3*7)+(2*4)+(1*8)=144
144 % 10 = 4
So 39087-48-4 is a valid CAS Registry Number.
InChI:InChI=1/2C10H11ClO3.Ca/c2*1-10(2,9(12)13)14-8-5-3-7(11)4-6-8;/h2*3-6H,1-2H3,(H,12,13);/q;;+2/p-2