391-78-6 Usage
General Description
6-Fluoro-4-hydroxyquinoline is a chemical compound that belongs to the class of quinolines, which are heterocyclic compounds containing a benzene ring fused to a pyridine ring. It is a derivative of quinoline with a fluorine atom attached to the 6th position and a hydroxyl group attached to the 4th position of the ring. 6-FLUORO-4-HYDROXYQUINOLINE has potential as an antibacterial agent and has been studied for its antimicrobial properties. It is also used in organic synthesis as a building block for the preparation of various biologically active compounds. Additionally, 6-fluoro-4-hydroxyquinoline may have potential applications in the fields of medicine and pharmacology for the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 391-78-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 391-78:
(5*3)+(4*9)+(3*1)+(2*7)+(1*8)=76
76 % 10 = 6
So 391-78-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H6FNO/c10-6-1-2-8-7(5-6)9(12)3-4-11-8/h1-5H,(H,11,12)
391-78-6Relevant articles and documents
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Snyder et al.
, p. 371,373 (1947)
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ANTIMALARIAL COMPOUNDS WITH FLEXIBLE SIDE-CHAINS
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Page/Page column 8-9, (2009/04/24)
The present invention relates to novel compounds that are inhibitors of wild type and mutant dihydrofolate reductase (DHFR) of Plasmodium falciparum, which are useful for the treatment of malaria. It also relates to processes of making and using such compounds. The antimalarial compounds of the present invention have low toxicity to a host infected with the malarial parasite, and are potent when administered in pharmaceutical compositions.
4-Piperidino-2-phenylquinolines
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, (2008/06/13)
Disclosed are compounds of the formula STR1 wherein: R1 and R2 may be either the same or different and each is hydrogen or lower alkyl; and wherein R3 and R4 may be either the same or different and each is hydrogen, halogen, or lower alkyl, with the proviso that R3 and R4 cannot both be hydrogen. These compounds are useful as anticonvulsant or anxiolytic agents.
