393105-53-8 Usage
Description
2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic acid is a complex organic compound with a unique molecular structure. It is characterized by its indole-based core, with a benzyl group attached to the nitrogen atom at position 1, and a trifluoromethoxy-substituted phenyl group connected to the indole at position 5. The molecule also features a carboxylic acid group at position 2 and an oxo group at position 3, which contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic acid is used as a therapeutic agent for various medical conditions due to its ability to modulate biological processes and target specific receptors or enzymes. Its unique structure allows it to interact with cellular components, making it a promising candidate for the development of new drugs.
Used in Chemical Research:
2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic aci d is also utilized in chemical research as a starting material or intermediate for the synthesis of more complex molecules with potential applications in various fields, such as materials science, agrochemistry, and environmental science.
Used in Drug Delivery Systems:
2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic acid can be employed in the development of novel drug delivery systems to improve the bioavailability, targeting, and efficacy of therapeutic agents. Its chemical properties may allow for the creation of innovative formulations, such as nanoparticles or liposomes, for targeted drug delivery.
Used in Diagnostic Applications:
The unique structure and properties of 2-[1-benzyl-5-[4-(trifluoromethoxy)phenyl]indol-3-yl]-2-oxo-acetic acid may also find use in the development of diagnostic tools, such as imaging agents or biosensors, for detecting and monitoring various diseases and conditions.
Biochem/physiol Actions
Tiplaxtinin has high oral bioavailability. It is metabolically stable and shows large safety multiples in animal toxicology studies. Tiplaxtinin can be easily synthesized in bulk quantities. This drug also reduces diet-induced obesity in mice.
Check Digit Verification of cas no
The CAS Registry Mumber 393105-53-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,3,1,0 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 393105-53:
(8*3)+(7*9)+(6*3)+(5*1)+(4*0)+(3*5)+(2*5)+(1*3)=138
138 % 10 = 8
So 393105-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C24H16F3NO4/c25-24(26,27)32-18-9-6-16(7-10-18)17-8-11-21-19(12-17)20(22(29)23(30)31)14-28(21)13-15-4-2-1-3-5-15/h1-12,14H,13H2,(H,30,31)
393105-53-8Relevant articles and documents
Regiocontrolled Direct C?H Arylation of Indoles at the C4 and C5 Positions
Yang, Youqing,Gao, Pan,Zhao, Yue,Shi, Zhuangzhi
, p. 3966 - 3971 (2017/03/27)
An effective and practical strategy has been established for the direct and site-selective arylation of indoles at the C4 and C5 positions with the aid of a readily accessible, cheap, and removable pivaloyl directing group at the C3 position. This transfo
Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: Design, synthesis, and preclinical characterization
Elokdah, Hassan,Abou-Gharbia, Magid,Hennan, James K.,McFarlane, Geraldine,Mugford, Cheryl P.,Krishnamurthy, Girija,Crandall, David L.
, p. 3491 - 3494 (2007/10/03)
Indole oxoacetic acid derivatives were prepared and evaluated for in vitro binding to and inactivation of human plasminogen activator inhibitor-1 (PAI-1). SAR based on biochemical, physiological, and pharmacokinetic attributes led to identification of tip
