394-66-1 Usage
General Description
5-Fluoroisoquinoline is an organic chemical compound with the molecular formula C9H6FN. It is a fluorinated derivative of isoquinoline, a heterocyclic aromatic compound. 5-Fluoroisoquinoline is used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It has potential applications in drug design and discovery as it exhibits unique pharmacological properties. The fluorine substitution in the isoquinoline ring can modulate the biological activity of molecules, making 5-Fluoroisoquinoline a valuable building block for the development of new drugs and biologically active compounds. Additionally, it is also used as a precursor in the production of novel materials and dyes.
Check Digit Verification of cas no
The CAS Registry Mumber 394-66-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 394-66:
(5*3)+(4*9)+(3*4)+(2*6)+(1*6)=81
81 % 10 = 1
So 394-66-1 is a valid CAS Registry Number.
394-66-1Relevant articles and documents
FLUORINATION OF ORGANIC COMPOUNDS
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Paragraph 00207, (2015/05/05)
Methods for fluorinating organic compounds utilizing a novel organic reagent are described herein. The invention further discloses the utility of this reagent for incorporation of the 18 F isotope into hydroxyl group -containing organic molecules for PET imaging studies. Preparation of the reagents is described along with isolable intermediate structures from reaction of the reagent with a hydroxyl group-containing organic molecule.
PhenoFluor: Practical synthesis, new formulation, and deoxyfluorination of heteroaromatics
Fujimoto, Teppei,Becker, Fabian,Ritter, Tobias
supporting information, p. 1041 - 1044 (2014/11/07)
We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.
