39416-48-3Relevant articles and documents
Ammonium hydrotribromide salts as convenient and selective brominating agents of aryl methyl ketones
Badali, Mohammad,Khalafy, Jabbar,Alidoost, Elnaz,Aghazadeh, Masomeh
, p. 859 - 863 (2016/11/21)
A simple and improved protocol for the α-monobromination of acetophenone and acetyl carbazole derivatives using different ammonium hydrotribromide salts under mild reaction condition was described.
A peptide bromoiodinane approach for asymmetric bromolactonization
Whitehead, Daniel C.,Fhaner, Matthew,Borhan, Babak
supporting information; experimental part, p. 2288 - 2291 (2011/05/16)
A series of 37 peptides containing an iodo-aryl amide active site were generated by means of both solid phase and conventional synthesis. These peptides were screened for asymmetric induction in the bromolactonization of 4-phenyl-4-pentenoic acid based on the generation of chiral bromoiodinane bromenium sources. The study culminated in the discovery of a tri-peptide iodo-aryl amide that effected the desired bromolactonization in quantitative conversion with 24% ee. The experiments disclosed herein provided valuable insight that ultimately facilitated the development of more synthetically useful enantioselective halocyclization methodology.
An environmentally benign synthesis of organic ammonium tribromides (OATB) and bromination of selected organic substrates by tetrabutylammonium tribromide (TBATB)
Chaudhuri, Mihir K.,Khan, Abu T.,Patel, Bhisma K.,Dey, Deepa,Kharmawophlang, Wancydora,Lakshmiprabha,Mandal, Gagan C.
, p. 8163 - 8166 (2007/10/03)
Stable crystalline organic ammonium tribromides (OATB), like Me4NBr3, Et4NBr3, Bu4NBr3, cetyltrimethylammonium tribromide, PyHBr3, can be readily synthesised from the reaction of the corresponding bromides with V2O5 and aqueous H2O2. Typically, TBATB, Bu4NBr3, brominates a variety of organic substrates rather easily under mild conditions. An activated aromatic ring is selectively brominated in the presence of an olefinic double bond.
