394655-11-9 Usage
Description
2-Phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine is a chemical compound belonging to the benzodiazepine class, characterized by its molecular formula C15H16N2. It is a psychoactive drug known for its sedative, hypnotic, anxiolytic, and muscle relaxant properties. 2-PHENYL-2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE acts on the central nervous system, particularly the gamma-aminobutyric acid (GABA) receptors, to produce its therapeutic effects. It is commonly used in the pharmaceutical industry for the synthesis of various drugs, such as sedatives and anxiolytics. However, it is important to handle this compound with caution as it can be habit-forming and may have potential side effects if not used properly.
Uses
Used in Pharmaceutical Industry:
2-Phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine is used as an intermediate compound for the synthesis of various drugs, specifically sedatives and anxiolytics. Its action on the central nervous system and GABA receptors allows for the development of medications that can effectively treat anxiety, insomnia, and other related conditions.
Used in Research and Development:
This benzodiazepine derivative is also utilized in research and development for the discovery and improvement of new psychoactive drugs. Its unique properties and interactions with the central nervous system make it a valuable tool for studying the mechanisms of action and potential therapeutic applications in various neurological and psychiatric disorders.
Used in Quality Control and Standardization:
2-Phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine can be employed as a reference compound in quality control and standardization processes within the pharmaceutical industry. It helps ensure the consistency, purity, and potency of benzodiazepine-based medications, contributing to the overall safety and efficacy of these drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 394655-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,4,6,5 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 394655-11:
(8*3)+(7*9)+(6*4)+(5*6)+(4*5)+(3*5)+(2*1)+(1*1)=179
179 % 10 = 9
So 394655-11-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2/c1-2-6-12(7-3-1)13-10-11-16-14-8-4-5-9-15(14)17-13/h1-9,13,16-17H,10-11H2
394655-11-9Relevant articles and documents
Direct and Enantioselective Synthesis of N?H-Free 1,5-Benzodiazepin-2-ones by an N-Heterocyclic Carbene Catalyzed [3+4] Annulation Reaction
Fang, Chao,Cao, Jing,Sun, Kewen,Zhu, Jindong,Lu, Tao,Du, Ding
, p. 2103 - 2108 (2018)
An NHC-catalyzed formal [3+4] annulation of α,β-unsaturated acylazoliums with protecting-group-free aryl 1,2-diamines was developed for a direct and highly enantioselective synthesis of 4-aryl N?H-free 1,5-benzodiazepin-2-ones. This methodology offers an efficient and rapid access to a wide range of enantioenriched target compounds from easily accessible starting materials. The protocol is also scalable and the desired products can easily undergo subsequent N-functionalization to afford diverse N-substituted derivatives. Additionally, a mechanism was proposed to explain the high enantioselectivity in this process.
