395-64-2

Basic information

• Product Name: 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE
• Synonyms: 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE;2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE, 97;2,5-Bis(trifluoromethyl)benzaldehyde 98%;2,5-Bis(trifluoromethyl)benzaldehyde98%
• CAS NO: 395-64-2
• Molecular Formula: C₉H₄F₆O
• Molecular Weight: 242.12
• EINECS: 1312995-182-4
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Aldehydes;C9;Carbonyl Compounds;Fluorine series
• Mol File: 395-64-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 137
• Flash Point: 157
• Appearance: /
• Density: 1.468
• Vapor Pressure: 0.317mmHg at 25°C
• Refractive Index: 1.421
• Storage Temp.: Room temperature.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE(395-64-2)
• EPA Substance Registry System: 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE(395-64-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37-36
• WGK Germany: 3
• Hazardous Substances Data: 395-64-2(Hazardous Substances Data)

Usage

General Description

2,5-Bis(trifluoromethyl)benzaldehyde is a chemical compound with the molecular formula C9H4F6O. It is a colorless liquid that is used in the synthesis of various organic compounds and as a building block in the production of pharmaceuticals and agrochemicals. 2,5-BIS(TRIFLUOROMETHYL)BENZALDEHYDE is known for its strong aromatic odor and is highly reactive due to the presence of the aldehyde functional group. It is widely used as an intermediate in the production of fine chemicals and has applications in the fields of materials science, pharmaceuticals, and agrochemicals. Additionally, 2,5-Bis(trifluoromethyl)benzaldehyde is also used as a flavoring agent and fragrance ingredient in the cosmetic and food industries. Due to its versatility and wide range of applications, this compound is of interest to researchers and industries alike.

InChI:InChI=1/C9H4F6O/c10-8(11,12)6-1-2-7(9(13,14)15)5(3-6)4-16/h1-4H

Upstream product

• 51012-27-2 2,5-bis(trifluoromethyl)benzonitrile 
• 175135-01-0 2-phenoxynicotinic acid hydrazide 

Downstream Products

• 869318-88-7 N-{(1E)-[2,5-bis(trifluoromethyl)phenyl]methylene}-2-methylpropane-2-sulfiamide 
• 53130-46-4 2,5-Bis(trifluoromethyl)benzamid 
• 1314797-82-4 C₁₈H₁₈F₆O₆ 
• 1159567-10-8 6-[4-(2,5-Bis-trifluoromethyl-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one 
• 59664-29-8 2-methyl-4-(2',5'-ditrifluoromethylphenyl)-1,4-dihydropyridine-3,5,6-tricarboxylic acid triethyl ester 
• 848863-58-1 (E,E)-1,4-di(2,5-bis(trifluoromethyl)phenyl)-1,3-butadiene 
• 861897-70-3 (E)-3-(2,5-Bis-trifluoromethyl-phenyl)-propenal 

Relevant articles and documents

ALPHA-(TRIFLUOROMETHYL-SUBSTITUTED ARYLOXY, ARYLAMINO, ARYLTHIO OR ARYLMETHYL)-TRIFLUOROMETHYL-SUBSTITUTED PHENYLACETIC ACIDS AND DERIVATIVES AS ANTIDIABETIC AGENTS

Compounds having a formula (1) or a pharmaceutically acceptable salt or prodrug thereof, are provided, and are useful for the treatment of metabolic disorders.

Process for producing trifluoromethylbenzylamines

The present invention relates to a process for producing a trifluoromethylbenzylamine represented by the general formula (1). This process includes the step of reducing an oxime represented by the general formula (2), where R1represents hydrogen atom, a halogen atom selected from the group consisting of fluorine, chlorine, bromine and iodine, or trifluoromethyl group, where R1is defined as above, and R2represents hydrogen atom, an alkyl group or an aralkyl group. With this process, the trifluoromethylbenzylamine can be produced with high selectivity.