39588-47-1

Basic information

• Product Name: 3-Ethyl-5,5-diphenylhydantoin
• Synonyms: 3-Ethyl-5,5-diphenyl-2,4-imidazolidinedione;3-Ethyl-5,5-diphenylhydantoin
• CAS NO: 39588-47-1
• Molecular Formula: C₁₇H₁₆N₂O₂
• Molecular Weight: 0
• Mol File: 39588-47-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Ethyl-5,5-diphenylhydantoin(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethyl-5,5-diphenylhydantoin(39588-47-1)
• EPA Substance Registry System: 3-Ethyl-5,5-diphenylhydantoin(39588-47-1)

Safety Data

• Hazardous Substances Data: 39588-47-1(Hazardous Substances Data)

Upstream product

• 64-67-5 diethyl sulfate 
• 57-41-0 phenythoin 
• 75-03-6 ethyl iodide 
• 625-52-5 N-Ethylurea 
• 134-81-6 benzil 
• 74-96-4 ethyl bromide 
• 75-00-3 chloroethane 
• 78451-65-7 S-ethyl-5,5'-diphenyl-2-thiohydantoin 
• 21083-47-6 5,5-diphenyl-2-thioxoimidazolidin-4-one 

Downstream Products

• 99702-67-7 1-Benzyl-3-ethyl-5,5-diphenyl-imidazolidine-2,4-dione 
• 99702-66-6 ethyl 3-ethyl-5,5-diphenyl-1-hydantoin acetate 
• 99702-68-8 1-Allyl-3-ethyl-5,5-diphenyl-imidazolidine-2,4-dione 
• 99705-79-0 3-Ethyl-1-oxiranylmethyl-5,5-diphenyl-imidazolidine-2,4-dione 

Relevant articles and documents

New aspects of reactions of methyl (thio)ureas with benzil

New pathways of reaction between 1-methylthiourea or 1-methylurea and benzil bring about new derivatives of (2S*,3aR*,6aS*)-perhydro-3aH-[1,3]dioxolo[4,5-d]imidazole and racemic (4S*,5R*)-4-alkoxy-5-hydroxy-1-methyl-4,5-diphenylimidazolidine-2-thiones. So

Solvent effects on the structure-activity relationship of phenytoin-like anticonvulsant drugs

The absorption spectra of nine compounds structurally related to phenytoin (5,5-diphenylhydantoin) were recorded in twelve solvents over the range of 200 to 400 nm. The effects of solvent dipolarity/polarizability and solvent/solute hydrogen bonding interactions were analyzed by means of the linear solvation energy relationship (LSER) concept proposed by Kamlet and Taft. The lipophilic activity of the investigated hydantoins was estimated by calculation of their log 10 P values. The calculated values of log 10 P were correlated with the ratio of the contributions of specific and non-specific solute/solvent interactions. The correlation equations were combined with the corresponding ED50 values to generate new equations that demonstrate exact relationship between solute/solvent interactions and the structure-activity parameters.

A high-yield selective N(3)-alkylation process of hydantoins using dimethylformamide dialkyl acetals

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