39615-34-4

Basic information

• Product Name: CYCLOPROPYL 2-METHYLPHENYL KETONE
• Synonyms: CYCLOPROPYL 2-METHYLPHENYL KETONE;CYCLOPROPYL(2-METHYLPHENYL)METHANONE
• CAS NO: 39615-34-4
• Molecular Formula: C₁₁H₁₂O
• Molecular Weight: 160.21
• Mol File: 39615-34-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 254.617°C at 760 mmHg
• Flash Point: 102.571°C
• Appearance: /
• Density: 1.093g/cm³
• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CYCLOPROPYL 2-METHYLPHENYL KETONE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPROPYL 2-METHYLPHENYL KETONE(39615-34-4)
• EPA Substance Registry System: CYCLOPROPYL 2-METHYLPHENYL KETONE(39615-34-4)

Safety Data

• Hazardous Substances Data: 39615-34-4(Hazardous Substances Data)

Usage

General Description

CYCLOPROPYL 2-METHYLPHENYL KETONE is a chemical compound with the molecular formula C11H12O. It is a ketone that contains a cyclic structure and a methylphenyl group. This chemical is often used as a building block in the synthesis of pharmaceuticals and other organic compounds. It is known for its strong odor and is commonly used as a flavor and fragrance ingredient. Additionally, it has been studied for its potential use in the development of new materials and applications in the field of organic chemistry.

InChI:InChI=1/C11H12O/c1-8-4-2-3-5-10(8)11(12)9-6-7-9/h2-5,9H,6-7H2,1H3

Upstream product

• 925430-09-7 tricyclopropylbismuthane 
• 615-37-2 ortho-methylphenyl iodide 
• 201230-82-2 carbon monoxide 
• 95-46-5 2-methylphenyl bromide 
• 147356-78-3 cyclopropanecarboxylic acid N-methoxy-N-methylamide 
• 932-31-0 ortho-tolylmagnesium bromide 
• 3469-06-5 benzocyclobutenone 
• 1563118-44-4 1-cyclopropylbenzocycyclobutenol 
• 130250-61-2 2-methyl-N-methoxy-N-methylbenzamide 
• 23719-80-4 cyclopropylmagnesium bromide 
• 14633-95-5 triphenylphosphonium cyclopropylide 
• 7732-18-5 water 
• 108-86-1 bromobenzene 
• 765-43-5 Cyclopropyl methyl ketone 

Downstream Products

• 1140910-91-3 C₁₇H₂₅BO₃ 
• 1236375-84-0 C₁₁H₁₄O 
• 193898-01-0 1,1-bis(2-methylphenyl)-4-bromo-1-butene 
• 39615-35-5 1-Cyclopropyl-2-phenyl-1-o-tolyl-ethanol 

Relevant articles and documents

Synthesis and photosensitized oxygenation of cyclopropylidenecyclobutenes

Cyclopropylidenecyclobutenes and -cyclobutanes were conveniently prepared using the Petasis titanocene approach. The cyclobutenes were unreactive to singlet oxygen, reacting sluggishly via a photoinitiated free radical autooxidative epoxidation process, to yield the corresponding spiroketones. By contrast, cyclopropylidenecyclobutanes react rapidly with 1O 2, via an 'ene' process, initially generating a cyclopropyl hydroperoxide, which proceeds to products via Hock cleavage. The inertness of cyclopropylidenecyclobutenes to a 1O2 'ene' reaction mode may be attributed to the fact that it would require the formation of the relatively high energy cyclobutadiene moiety.

B(C6F5)3-Catalyzed Hydrosilylation of Vinylcyclopropanes

A hydrosilylation of vinylcyclopropanes (VCPs) catalyzed by the strong boron Lewis acid B(C6F5)3 is reported. For the majority of VCPs, little or no ring opening of the cyclopropyl unit is observed. Conversely, for VCPs with bulky R groups, such as ortho-substituted aryl rings or branched alkyl residues, ring opening is the exclusive reaction pathway. This finding is explained by the thwarted hydride delivery to a sterically shielded, β-silicon-stabilized cyclopropylcarbinyl cation intermediate.

Palladium-Catalyzed Carbonylative Cross-Coupling Reaction between Aryl(Heteroaryl) Iodides and Tricyclopropylbismuth: Expedient Access to Aryl Cyclopropylketones

The carbonylative cross-coupling reaction between aryl and heteroaryl iodides and tricyclopropylbismuth is reported. The reaction is catalyzed by (SIPr)Pd(allyl)Cl, a NHC-palladium(II) catalyst, operates under 1 atm of carbon monoxide and tolerates a wide range of functional groups. The use of lithium chloride was found to provide higher yields of the desired aryl cyclopropylketones. The conditions were also applied to the carbonylative cross-coupling of an iodoalkene to afford the corresponding alkenyl cyclopropylketone.