3970-40-9

Basic information

• Product Name: 2-CHLORO-3-NITROTOLUENE
• Synonyms: 2-CHLORO-3-NITROTOLUENE 98%;2-chloro-1-methyl-3-nitrobenzene;2-chloro-1-methyl-3-nitro-benzene;2-Cloro-3-nitrotoluene;2-CHLORO-3-NITROTOLU;2-Chloro-3-methylnitrobenzene, 2-Chloro-1-methyl-3-nitrobenzene;2-Chloro-3-nit;2-CHLORO-3-NITROTOLUENE
• CAS NO: 3970-40-9
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58
• EINECS: 223-591-9
• Product Categories: API intermediates;Chlorine Compounds;Nitro Compounds;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks;Aromatic Hydrocarbons (substituted) & Derivatives
• Mol File: 3970-40-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 21 °C(lit.)
• Boiling Point: 147 °C25 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.298 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.557(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-CHLORO-3-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-NITROTOLUENE(3970-40-9)
• EPA Substance Registry System: 2-CHLORO-3-NITROTOLUENE(3970-40-9)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-50
• Safety Statements: 61
• RIDADR: UN 2433 6.1/PG 3
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 3970-40-9(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-nitrotoluene is a chemical compound that is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is a derivative of toluene, with a chlorine atom and a nitro group attached to the aromatic ring. 2-Chloro-3-nitrotoluene is a yellow crystalline solid that is insoluble in water and has a strong odor. It is primarily used as an intermediate in the production of dyes, fluorescent brighteners, and other organic compounds. The compound is also used as a chemical reagent in various industrial processes and is known for its mild skin and eye irritation properties. Additionally, 2-Chloro-3-nitrotoluene is a potential environmental contaminant and should be handled and disposed of with proper care to prevent adverse effects on human health and the environment.

InChI:InChI=1/C7H6ClNO2/c1-5-3-2-4-6(7(5)8)9(10)11/h2-4H,1H3

Upstream product

• 570-24-1 2-Methyl-6-nitroaniline 
• 95-49-8 2-methylchlorobenzene 
• 7697-37-2 nitric acid 
• 99-08-1 1-methyl-3-nitrobenzene 
• 7782-50-5 chlorine 
• 13506-76-8 2-methyl-6-nitrobenzoic acid 
• 13073-29-5 2-methyl-6-nitrophenol 
• 95-48-7 ortho-cresol 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 59907-22-1 N-(2-methyl-6-nitrophenyl)acetamide 

Downstream Products

• 18102-29-9 2-methyl-6-nitroanisole 
• 18905-50-5 2-chloro-1-methyl-3,5-dinitrobenzene 
• 29027-17-6 2-chloro-3-methylaniline 
• 54237-36-4 7-methyl-3H-benzothiazole-3-thione 
• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 80689-19-6 7-Methyl-3H-benzothiazol-2-one 
• 93566-50-8 3-<2-(2-methyl-6-nitrophenoxy)phenyl>prop-1-ene 
• 89642-16-0 α-bromo-2-chloro-3-nitrotoluene 
• 58755-57-0 2-chloro-3-nitrobenzaldehyde 
• 154078-75-8 2-methyl-6-nitrobenzenethiol 
• 92149-67-2 2,2'-Dinitro-6,6'-dimethyl-diphenylether 
• 1885-76-3 2-cyano-3-nitrotoluene 
• 622861-44-3 2-[(E)-2-(2-chloro-3-nitrophenyl)ethenyl]-5-methoxy-1H-indole 
• 622861-46-5 4-(2-chloro-3-nitrophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione 

Relevant articles and documents

Synthesis method of 2-fluoro-3-nitrobenzoic acid intermediate raw material

The invention discloses a synthesis method of a 2-fluoro-3-nitrobenzoic acid intermediate raw material. The invention provides a novel synthesis route, and an important medical intermediate can be rapidly and conveniently prepared from cheap and easily available raw materials. The process method comprises the following steps: starting from o-methylphenol, carrying out nitration reaction to selectively generate a key intermediate 2-methyl-6-nitrophenol, carrying out hydroxyl chlorination to generate 2-chloro-3-nitrotoluene, then carrying out fluorination reaction to generate 2-fluoro-3-nitrotoluene, and finally oxidizing methyl under the action of an oxidant to generate 2-fluoro-3-nitrobenzoic acid. The method is not only high in yield, but also suitable for large-scale production.

INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, methods for use as Bruton's tyrosine kinase and methods of production.

Quinoline compound containing perfluoroalkyl substituent, as well as preparation method and application of quinoline compound

The invention disclose a quinoline compound containing a perfluoroalkyl substituent, as shown in a general formula A-1, wherein the details of the definition of R2, R3, R4, R5, R6 and I are seen in the description. The invention further discloses a preparation method and application of the quinoline compound containing the perfluoroalkyl substituent. The quinoline compound containing the perfluoroalkyl substituent provided by the invention is suitable for agriculture insecticide.