39750-93-1

Basic information

• Product Name: 2-ADAMANTANECARBOXZALDEHYDE
• Synonyms: 2-ADAMANTANECARBOXZALDEHYDE;2-adaMantanecarboxaldehyde;2-Formyladamantane;Tricyclo[3.3.1.1(3,7)]decane-2-carboxaldehyde;tricyclo[3.3.1.13,7]decane-2-carbaldehyde;AdaMantane-2-carbaldehyde
• CAS NO: 39750-93-1
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.24414
• Mol File: 39750-93-1.mol
• Article Data: 19

Chemical Properties

• Melting Point: 158-160℃
• Boiling Point: 247.5±9.0℃ (760 Torr)
• Flash Point: 85.5±11.2℃
• Appearance: /
• Density: 1.124±0.06 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 2-ADAMANTANECARBOXZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ADAMANTANECARBOXZALDEHYDE(39750-93-1)
• EPA Substance Registry System: 2-ADAMANTANECARBOXZALDEHYDE(39750-93-1)

Safety Data

• Hazardous Substances Data: 39750-93-1(Hazardous Substances Data)

Usage

Uses

Adamantane-2-carbaldehyde can be used to treat tuberculosis.

InChI:InChI=1S/C11H16O/c12-6-11-9-2-7-1-8(4-9)5-10(11)3-7/h6-11H,1-5H2

Upstream product

• 68251-94-5 ω-(Bromomethylene)adamantane 
• 700-58-3 2-Adamantanone 
• 63830-94-4 Adamantan-2-oxiran-3-ylmethyltrimethylsilane 
• 84454-51-3 diethylmethyl<(tricyclo<3.3.1.1^3,7>decylidene)methoxy>silane 
• 412346-92-0 tert.-Butyl-epoxyadamantylidenacetat 
• 19066-22-9 2-acetoxyadamantane 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 29542-63-0 2-(methoxymethylene)adamantane 
• 50-00-0 formaldehyd 
• 337509-12-3 5-methoxy-5-methylspiro(Δ³-1,3,4-oxadiazolin-2,2'-tricyclo[3.3.1.1^3,7]decane) 
• 15897-81-1 adamantane-2-carboxylic acid 
• 1774-47-6 trimethylsulfoxonium iodide 
• 72590-63-7 2-(methoxymethylene)adamantane 
• 111922-77-1 2-Isocyanomethylene-adamantane 

Downstream Products

• 15897-81-1 adamantane-2-carboxylic acid 
• 151386-39-9 2-(adamant-2-ylmethyl)aminodiphenylamine 
• 53140-72-0 2-adamantyl(phenyl)methanol 
• 151620-70-1 1-N-(adamant-2-ylmethyl)-3-amino-2,4-dioxo-5-N-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 151386-40-2 1-(adamant-2-ylmethyl)-2,4-dioxo-5-phenyl-3-phenylhydrazono-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine 
• 1159912-95-4 C₂₃H₃₂ClFN₂ 
• 770-71-8 1-adamantanemethanol 
• 187091-99-2 2-(p-carbomethoxybenzoyl)-2-methyladamantane 
• 219812-06-3 2-(p-cyanobenzoyl)-2-methyladamantane 

Relevant articles and documents

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Ring-fused compound, pharmaceutical composition containing same and application of compound

The invention discloses a ring-fused compound, a preparation method thereof, pharmaceutical composition containing the compound and an application of the compound. A polycyclic compound (I) as well asan isomer, a prodrug, a stable isotopic derivative or pharmacologically acceptable salt of the compound (I) has the following structure. The polycyclic compound has good IDO1 and/or TDO2 inhibition functions, can effectively treat, relieve and/or prevent various diseases which are related with IDO1 and/or TDO2, such as cancer, virus infection, autoimmune diseases or the like.

Reduction of N,N-Dimethylcarboxamides to Aldehydes by Sodium Hydride–Iodide Composite

A new and concise protocol for selective reduction of N,N-dimethylamides into aldehydes was established using sodium hydride (NaH) in the presence of sodium iodide (NaI) under mild reaction conditions. The present protocol with the NaH-NaI composite allows for reduction of not only aromatic and heteroaromatic but also aliphatic N,N-dimethylamides with wide substituent compatibility. Retention of α-chirality in the reduction of α-enantioriched amides was accomplished. Use of sodium deuteride (NaD) offers a new step-economical alternative to prepare deuterated aldehydes with high deuterium incorporation rate. The NaH-NaI composite exhibits unique chemoselectivity for reduction of N,N-dimethylamides over ketones.