39760-01-5

Basic information

• Product Name: N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE
• Synonyms: N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE
• CAS NO: 39760-01-5
• Molecular Formula: C₁₃H₁₆N₂O
• Molecular Weight: 216.28
• Mol File: 39760-01-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 487.8 °C at 760 mmHg
• Flash Point: 248.8 °C
• Appearance: /
• Density: 1.138 g/cm³
• CAS DataBase Reference: N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE(39760-01-5)
• EPA Substance Registry System: N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE(39760-01-5)

Safety Data

• Hazardous Substances Data: 39760-01-5(Hazardous Substances Data)

Usage

General Description

N-[2-(2-Methyl-1H-indol-3-yl)ethyl]acetamide is a chemical compound with the formula C14H18N2O. It is a derivative of acetamide and contains an indole ring. N-[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]ACETAMIDE is used in research and pharmaceutical applications due to its potential biological activity. It may function as a ligand for serotonin receptors or possess other pharmacological properties. Its structure and properties make it a valuable tool for investigating drug-receptor interactions and developing new drug candidates.

Upstream product

• 95-20-5 2-methyl-1H-indole 
• 142-26-7 2-acetylaminoethanol 
• 62005-48-5 N-acetylaminoacetaldehyde dimethyl acetal 
• 267899-36-5 1-(5-methyl-2,3-dihydro-pyrrol-1-yl)-ethanone 
• 872-32-2 2-methyl-1H-pyrroline 
• 7546-14-7 N-acetylpyridinium chloride 
• 17636-95-2 N-<(4-oxo)-1-pentyl>acetamide 
• 100-63-0 phenylhydrazine 

Downstream Products

• 2731-06-8 2-methyltryptamine 

Relevant articles and documents

Iridium-catalyzed direct synthesis of tryptamine derivatives from indoles: Exploiting N-protected β-amino alcohols as alkylating agents

The selective C3-alkylation of indoles with N-protected ethanolamines involving the "borrowing hydrogen" strategy is described. This method provides convenient and sustainable access to several tryptamine derivatives.

A one-pot three-component reaction for the preparation of highly functionalized tryptamines

We have developed a general one-pot method to provide highly functionalized tryptamine derivatives, via a Fischer indole type pathway. In this article, we demonstrate optimal conditions for a one-pot indole synthesis, allowing for the synthesis of a broad scope of 2-methyl tryptamine derivatives and a precursor for the synthesis of the core structure of some akuammiline alkaloids. Additionally, further modification of the indole products is described.