398456-87-6

Basic information

• Product Name: 2-Fluoro-4-methylsulfonylphenol
• Synonyms: 2-Fluoro-4-methylsulfonylphenol;2-fluoro-4-Methanesulfonylphenol;3-Fluoro-4-hydroxyphenyl methyl sulphone
• CAS NO: 398456-87-6
• Molecular Formula: C₇H₇FO₃S
• Molecular Weight: 190.1920832
• Mol File: 398456-87-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 92-94℃
• Boiling Point: 362.812 °C at 760 mmHg
• Flash Point: 173.223 °C
• Appearance: /
• Density: 1.421 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Fluoro-4-methylsulfonylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-4-methylsulfonylphenol(398456-87-6)
• EPA Substance Registry System: 2-Fluoro-4-methylsulfonylphenol(398456-87-6)

Safety Data

• Hazardous Substances Data: 398456-87-6(Hazardous Substances Data)

Usage

General Description

2-Fluoro-4-methylsulfonylphenol is a specific type of organic compound known as an aryl methyl sulfonyl compound. This chemical consists of a benzene ring with a hydroxyl group (-OH), a fluoro (-F) and a methylsulfonyl group (-SO2CH3) attached at the second, fourth and fourth positions respectively. It is used in scientific research and chemical reactions that necessitate a phenol with fluorine and sulfone groups. However, its specific properties and safety measures aren't largely studied, hence requires careful handling to avoid potential hazards. It is essential in organic synthesis. Like other chemicals, it needs proper storage and needs to be handled with care.

InChI:InChI=1/C7H7FO3S/c1-12(10,11)5-2-3-7(9)6(8)4-5/h2-4,9H,1H3

Upstream product

• 2105-94-4 4-bromo-2-fluorophenol 
• 20277-69-4 sodium methansulfinate 
• 2357-52-0 3-fluoro-4-methoxyphenyl bromide 
• 66624-36-0 2-fluoro-1-methoxy-4-(methylsulfanyl)benzene 
• 20951-14-8 2-fluoro-1-methoxy-4-(methylsulfonyl)benzene 

Downstream Products

• 779331-21-4 trifluoromethanesulfonic acid 2-fluoro-4-(methylsulfonyl)phenyl ester 
• 1236281-74-5 tert-butyl 4-[5-fluoro-4-(2-fluoro-4-mesylphenoxy)pyrrolo[2,3-d]pyrimidin-7-yl]piperidine-1-carboxylate 
• 1403676-73-2 8-((2-fluoro-4-(methylsulfonyl)phenoxy)methyl)-1,4-dioxaspiro[4.5]decane 

Relevant articles and documents

NOVEL PYRROLOY2,3-d¨PYRIMIDINE COMPOUND

Disclosed is a novel pyrrolo[2,3-d]pyrimidine compound represented by formula [I] or a pharmacologically acceptable salt thereof, which has a GPR119 receptor agonistic activity and is useful for a pharmaceutical. In formula [I], E represents a group repre

SYNTHESIS OF METHYLSULPHONYL BENZENE COMPOUNDS

The present invention relates to a process for the synthesis of l-substituted-2-fluoro-4- methylsulfonylphenyl compounds.

1,2,4-OXADIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel 1,2,4-oxadiazole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.