398476-90-9

Basic information

• Product Name: 2(1H)-Isoquinolinecarboxylic acid, 3-[[[2'-[[(1,1-dimethylethyl)amino]sulfonyl][1,1'-biphenyl]-4-yl]amino]carb onyl]-3,4-dihydro-6-hydroxy-, 1,1-dimethylethyl ester, (3S)-
• CAS NO: 398476-90-9
• Molecular Formula: C31H37N3O6S
• Molecular Weight: 579.717
• Mol File: 398476-90-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(1H)-Isoquinolinecarboxylic acid, 3-[[[2'-[[(1,1-dimethylethyl)amino]sulfonyl][1,1'-biphenyl]-4-yl]amino]carb onyl]-3,4-dihydro-6-hydroxy-, 1,1-dimethylethyl ester, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Isoquinolinecarboxylic acid, 3-[[[2'-[[(1,1-dimethylethyl)amino]sulfonyl][1,1'-biphenyl]-4-yl]amino]carb onyl]-3,4-dihydro-6-hydroxy-, 1,1-dimethylethyl ester, (3S)-(398476-90-9)
• EPA Substance Registry System: 2(1H)-Isoquinolinecarboxylic acid, 3-[[[2'-[[(1,1-dimethylethyl)amino]sulfonyl][1,1'-biphenyl]-4-yl]amino]carb onyl]-3,4-dihydro-6-hydroxy-, 1,1-dimethylethyl ester, (3S)-(398476-90-9)

Safety Data

• Hazardous Substances Data: 398476-90-9(Hazardous Substances Data)

Upstream product

• 150691-04-6 2-(tert-butylamino)sulfonylphenylboronic acid 
• 98-09-9 benzenesulfonyl chloride 
• 2512-24-5 N-tert-butylbenzenesulfonamide 
• 193006-34-7 4-(2'-tert-butylaminosulfonylphenyl)aniline 

Relevant articles and documents

Design, synthesis, and SAR of amino acid derivatives as factor Xa inhibitors1

A series of potent and selective factor Xa inhibitors was synthesized using various readily available amino acids as central templates. The most potent compound displays IC50 of 3 nM.