4000-72-0

Basic information

• Product Name: 1-(aminomethyl)cyclohexan-1-ol
• Synonyms: 1-(aminomethyl)cyclohexan-1-ol;1-AMINOMETHLCYCLOHEXANOL;1-(aminomethyl)cyclohexanol;1-(Aminomethyl)-1-cyclohexanol;Einecs 223-648-8
• CAS NO: 4000-72-0
• Molecular Formula: C₇H₁₅NO
• Molecular Weight: 129.2001
• EINECS: 223-648-8
• Mol File: 4000-72-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 122-123℃
• Boiling Point: 120-128℃ (18 Torr)
• Flash Point: 86.6 °C
• Appearance: /
• Density: 1.02 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 12.99±0.20(Predicted)
• CAS DataBase Reference: 1-(aminomethyl)cyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(aminomethyl)cyclohexan-1-ol(4000-72-0)
• EPA Substance Registry System: 1-(aminomethyl)cyclohexan-1-ol(4000-72-0)

Safety Data

• Hazardous Substances Data: 4000-72-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 12, p. 923, 1971 DOI: 10.1016/S0040-4039(01)96590-6Journal of the American Chemical Society, 73, p. 2359, 1951 DOI: /10.1021/ja01149a511

InChI:InChI=1/C7H15NO/c8-6-7(9)4-2-1-3-5-7/h9H,1-6,8H2

Upstream product

• 15344-39-5 1,2-epoxy-cyclohexanecarbonitrile 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 
• 108-85-0 1-bromocyclohexane 
• 13280-16-5 N-(diphenylmethylene)methylamine 
• 51411-46-2 1-(Diphenylmethylenaminomethyl)cyclohexanol 
• 185-69-3 1-aza-spiro[2.5]octane 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 239104-34-8 1-ethyl-6-methoxy-1H-pyrazolo[3,4-b]quinoline 
• 108-94-1 cyclohexanone 
• 123934-02-1 Benzyl-(1-hydroxy-cyclohex-2-enylmethyl)-carbamic acid benzyl ester 
• 123934-17-8 (4R,5S)-3-(1-Hydroxy-cyclohexylmethyl)-4,5-diphenyl-oxazolidin-2-one 
• 123934-01-0 Benzyl-(1-hydroxy-cyclohexylmethyl)-carbamic acid benzyl ester 

Downstream Products

• 21095-16-9 1-<(dimethylamino)methyl>cyclohexanol 
• 160446-31-1 N,N-dimethyl-2-<<(1-hydroxycyclohexyl)methyl>amino>acetamide 
• 15753-47-6 1-(hydroxymethyl)cyclohexanol 
• 502-42-1 cycloheptanone 
• 1037768-03-8 1-(((5-(3,7-dimethyl-5-(pentan-3-yl)-5H-pyrrolo[3,2-b]pyrazin-2-yl)-4-methylthiazol-2-yl)methylamino)methyl)cyclohexanol 
• 37150-63-3 1-(acetamidomethyl)cyclohexanol 
• 1227808-80-1 C₁₈H₁₉ClFN₃O₂ 
• 1268630-89-2 C₁₈H₂₅NO₃S 
• 1268631-16-8 C₂₄H₄₁NO₄SSi 
• 1268630-80-3 C₁₈H₂₇NO₄S 
• 58107-53-2 N-{(1-hydroxycyclohexyl)methyl}-4-methylbenzenesulfonamide 

Relevant articles and documents

A One-Pot Reaction toward the Diastereoselective Synthesis of Substituted Morpholines

The diastereoselective synthesis of various substituted morpholines has been achieved from vinyloxiranes and amino-alcohols under sequential Pd(0)-catalyzed Tsuji-Trost/Fe(III)-catalyzed heterocyclization. Using the same strategy, 2,6-, 2,5-, and 2,3-disubstituted as well as 2,5,6- and 2,3,5-trisubstituted morpholines were obtained in good to excellent yields and diastereoselectivities.

SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS

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Substituted N-cycloalkylmethyl-1H-pyrazolo(3,4-b)quinolin-4 amines and compositions and methods of use thereof

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