400073-98-5 Usage
General Description
1-METHYL-5-(4-METHYLPHENOXY)-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is a chemical compound with the molecular formula C19H17NO2. It is a pyrazole derivative that contains a carbonyl group attached to a 1-methyl-5-(4-methylphenoxy)-3-phenylpyrazole core structure. 1-METHYL-5-(4-METHYLPHENOXY)-3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE is commonly used in organic synthesis and medicinal chemistry as a building block for the preparation of various functionalized pyrazole compounds. It may also have potential applications in pharmaceutical research and as a chemical intermediate in the production of other organic compounds. Additionally, it is important to handle this compound with caution due to its potential health hazards and environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 400073-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,0,7 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 400073-98:
(8*4)+(7*0)+(6*0)+(5*0)+(4*7)+(3*3)+(2*9)+(1*8)=95
95 % 10 = 5
So 400073-98-5 is a valid CAS Registry Number.
400073-98-5Relevant articles and documents
Synthesis and evaluation of anticonvulsant activities of pyrazol semicarbazones. Part II
Song, Ming-Xia,Wu, Yi,Deng, Xian-Qing
, p. 800 - 808 (2016/09/23)
A series of 2-((5-aryloxy-1-methyl-3-methyl-1H-pyrazol-4-yl)methylene) hydrazinecarboxamides (6a-6l) and 2-((5-aryloxy-1-methyl-3-phenyl-1H-pyrazol-4-yl)methylene) hydrazinecarboxamides (7a-7l) were designed and synthesized. The maximal electroshock shock (MES) and subcutaneous pentylenetetrazole (sc-PTZ) seizure models in mice were used to evaluate the antiepileptic effect of compounds synthesized. Further, the acute neurotoxicity profile was also studied via the rotarod test. The results of sc-PTZ test indicate that a majority of compounds possessed anticonvulsant activity with long duration of protection effects. Among of them, compound 6k was found to be the most promising one, with an ED50 value of 20.4 mg/kg (in sc-PTZ model) and a PI value of 10.8, possessing higher anti-PTZ activity and wider safety margin than valproate and ethosuximide.
