400750-29-0

Basic information

• Product Name: Methyl 4-(1H-pyrazol-1-yl)benzoate
• Synonyms: Methyl 4-(1H-pyrazol-1-yl)benzoate;Methyl 4-(pyrazol-1-yl)benzoate
• CAS NO: 400750-29-0
• Molecular Formula: C11H10N2O2
• Molecular Weight: 202.2093
• Mol File: 400750-29-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 119～121℃
• Boiling Point: 319.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -0.36±0.10(Predicted)
• CAS DataBase Reference: Methyl 4-(1H-pyrazol-1-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-(1H-pyrazol-1-yl)benzoate(400750-29-0)
• EPA Substance Registry System: Methyl 4-(1H-pyrazol-1-yl)benzoate(400750-29-0)

Safety Data

• Hazardous Substances Data: 400750-29-0(Hazardous Substances Data)

Usage

General Description

Methyl 4-(1H-pyrazol-1-yl)benzoate is a chemical compound with the molecular formula C10H9N3O2. It is a derivative of pyrazole and benzoic acid, and it is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is a crystalline solid that is soluble in organic solvents and has a melting point of around 101-103°C. Methyl 4-(1H-pyrazol-1-yl)benzoate has potential biological activities and is being studied for its potential therapeutic applications. As a ester compound, it has wide applications in various fields due to its unique chemical and physical properties, making it an important compound in the chemical industry.

Upstream product

• 288-13-1 NH-pyrazole 
• 403-33-8 methyl 4-flurobenzoate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 619-44-3 methyl 4-iodobenzoate 

Downstream Products

• 143426-52-2 4-(1H-pyrazol-1-yl)phenylmethyl chloride 
• 1087329-20-1 (R)-tert-butyl 3-(4-(1H-pyrazol-1-yl)benzamido)pyrrolidine-1-carboxylate 

Relevant articles and documents

PYRROLIDINE GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein A, W, R3b, Z and p have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.

L -(-) -Quebrachitol as a Ligand for Selective Copper(0)-Catalyzed N-Arylation of Nitrogen-Containing Heterocycles

l-(-)-Quebrachitol (QCT) has been found as a ligand of copper powder for selective N-arylation of nitrogen-containing heterocycles with aryl halides. Furthermore, another potential catalytic system (copper powder/QCT/t-BuOK) was successfully adapted to unactivated aryl chlorides.

Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonists

On the basis of the previously reported benzimidazole 1,3′- bipyrrolidine benzamides (1), a series of related pyrrolidin-3-yl-N- methylbenzamides were synthesized and evaluated as H3 receptor antagonists. In particular, compound 32 exhibits pot