40108-65-4 Usage
Explanation
Different sources of media describe the Explanation of 40108-65-4 differently. You can refer to the following data:
1. The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. This describes the arrangement of atoms and bonds in the compound, including the triazine ring, phenyl group, and chlorophenylmethyl group.
3. Heterocyclic organic compound
3. The compound contains a ring structure with both carbon and non-carbon atoms, making it a heterocyclic compound.
4. Triazine ring
4. The compound has a triazine ring, which is a six-membered ring containing three nitrogen atoms and three carbon atoms.
5. Phenyl group attachment
5. One of the carbon atoms in the triazine ring is connected to a phenyl group, which is a six-membered aromatic ring with alternating single and double bonds.
6. Chlorophenylmethyl group attachment
6. The compound also has a chlorophenylmethyl group attached to the triazine ring. This group consists of a phenyl ring with a chlorine atom and a methyl group (CH3) attached to it.
7. Pharmaceutical research application
7. The compound is used as a building block or intermediate in the synthesis of biologically active molecules, which can be further developed into drugs or other pharmaceutical products.
8. Potential applications in drug or agrochemical development
8. Due to its unique structure and properties, the compound may be used in the development of new drugs or agrochemicals with specific biological activities.
9. Toxicological and environmental implications
9. The compound may have certain toxicological effects on living organisms and the environment, so proper handling, storage, and disposal procedures should be followed when working with it.
10. Proper handling and disposal procedures
10. When working with this compound, it is essential to follow safety guidelines and protocols to minimize the risk of exposure and potential harm to humans and the environment.
Chemical structure
1,2,4-Triazin-6(1H)-one, 5-[(4-chlorophenyl)methyl]-3-phenyl-
Check Digit Verification of cas no
The CAS Registry Mumber 40108-65-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,1,0 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40108-65:
(7*4)+(6*0)+(5*1)+(4*0)+(3*8)+(2*6)+(1*5)=74
74 % 10 = 4
So 40108-65-4 is a valid CAS Registry Number.
40108-65-4Relevant articles and documents
Design, synthesis, and biological evaluation of hydrazone incorporated 1,2,4-triazines as anticonvulsant agents
Amir, Mohammed,Ali, Israr,Hassan, Mohd. Zaheen,Mulakayala, Naveen
, p. 958 - 968 (2015/02/19)
New hydrazone incorporated triazines were designed and synthesized using an appropriate synthetic route with regard to essential pharmacophores, and evaluated for their anticonvulsant activity through maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole-induced seizure (scPTZ) screenings. Among the tested compounds, 4-[{2-(5-(3-chlorobenzyl)-3-phenyl-1,2,4-triazine-6-yl)hydrazono} methyl]-N,N-dimethylaniline 6k (MES ED50 54.31, scPTZ ED50 92.01) and 4-[{2-(5-(4-chlorobenzyl)-3-phenyl-1,2,4-triazine-6-yl)hydrazono}methyl]-N,N-dimethylaniline 6r (MES ED50 46.05, scPTZ ED50 83.90) emerged as the most active anticonvulsant agents having GABAergic effects. Compounds 6k and 6r also showed lesser CNS depressant effect than the standard drug carbamazepine. To obtain further insights into the binding interactions of these molecules, molecular docking studies were carried out.
