4014-60-2
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Basic information
- Product Name: 2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione
- Synonyms:
- CAS NO:4014-60-2
- Molecular Formula: C14H18N2O4
- Molecular Weight: 278.3037
- EINECS: N/A
- Product Categories: N/A
- Mol File: 4014-60-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 446.2°C at 760 mmHg
- Flash Point: 223.7°C
- Appearance: N/A
- Density: 1.33g/cm3
- Vapor Pressure: 3.7E-08mmHg at 25°C
- Refractive Index: 1.596
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione(CAS DataBase Reference)
- NIST Chemistry Reference: 2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione(4014-60-2)
- EPA Substance Registry System: 2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione(4014-60-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 4014-60-2(Hazardous Substances Data)
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4014-60-2 Usage
General Description
2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione, also known as BCNU, is a potent alkylating agent used in chemotherapy to treat various types of cancer, including brain tumors, Hodgkin's disease, and multiple myeloma. It works by crosslinking DNA, preventing the replication and transcription of the genetic material within cancer cells, ultimately leading to cell death. BCNU is administered intravenously and has a relatively long half-life in the body, allowing for a sustained anti-cancer effect. However, it can also cause severe side effects, including bone marrow suppression, gastrointestinal issues, and potential damage to the heart and lungs, so its use is carefully monitored and managed by healthcare professionals.Check Digit Verification of cas no
The CAS Registry Mumber 4014-60-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,1 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.Calculate Digit Verification of CAS Registry Number 4014-60:
(6*4)+(5*0)+(4*1)+(3*4)+(2*6)+(1*0)=52
52 % 10 = 2
So 4014-60-2 is a valid CAS Registry Number.
4014-60-2Upstream product
4014-60-2Downstream Products
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2,5-bis(aziridin-1-yl)-3,6-diethoxycyclohexa-2,5-diene-1,4-dione
