401593-45-1Relevant articles and documents
Total synthesis of marine diterpenoid stolonidiol
Miyaoka, Hiroaki,Baba, Tomohiro,Mitome, Hidemichi,Yamada, Yasuji
, p. 9233 - 9236 (2001)
Marine dolabellane diterpenoid stolonidiol was synthesized from L-ascorbic acid. The method for this total synthesis involves formation of the bicyclo[2.2.1]heptane derivative using a diastereoselective sequential Michael reaction, formation of cyclopentane derivative by the retro-aldol reaction and construction of an 11-membered carbocyclic ring through the intramolecular Horner-Wadsworth-Emmons reaction.