40277-59-6 Usage
Structure
2-((5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)acetic acid
Contains sulfur
Yes
Use in laboratory research
Yes, as a potential ligand for various biological targets
Potential pharmacological properties
Yes, may be a candidate for drug development
Hazardous if not properly managed
Yes, important to handle with care
Further research needed
Yes, to fully understand its properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 40277-59-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,2,7 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 40277-59:
(7*4)+(6*0)+(5*2)+(4*7)+(3*7)+(2*5)+(1*9)=106
106 % 10 = 6
So 40277-59-6 is a valid CAS Registry Number.
40277-59-6Relevant articles and documents
Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase
Tarver, James E.,Pabba, Praveen K.,Barbosa, Joseph,Han, Qiang,Gardyan, Michael W.,Brommage, Robert,Thompson, Andrea Y.,Schmidt, James M.,Wilson, Alan G.E.,He, Wei,Lombardo, Victoria K.,Carson, Kenneth G.
, p. 1525 - 1528 (2016/07/27)
A group of small molecule thienopyrimidine inhibitors of Notum Pectinacetylesterase are described. We explored both 2-((5,6-thieno[2,3-d]pyrimidin-4-yl)thio)acetic acids and 2-((6,7-thieno[3,2-d]pyrimidin-4-yl)thio)acetic acids. In both series, highly potent, orally active Notum Pectinacetylesterase inhibitors were identified.
