40290-32-2

Basic information

• Product Name: 1,2-DIPALMITOYL-RAC-GLYCEROL
• Synonyms: DL-DIPALMITIN;DL-ALPHA,BETA-DIPALMITIN;DL-1,2-DIPALMITIN;DL-1,2-DIPALMITOYLGLYCEROL;(+/-)-1,2-DIPALMITIN;1,2-DIPALMITOYL-RAC-GLYCEROL;1,2-DIHEXADECANOYL-RAC-GLYCEROL;RAC-1,2-DIPALMITOYLGLYCEROL
• CAS NO: 40290-32-2
• Molecular Formula: C35H68O5
• Molecular Weight: 568.91
• EINECS: 254-870-3
• Product Categories: Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives;Glycerolipids;Analytical Reagents;Analytical/Chromatography;Biochemicals and Reagents;Building Blocks;C12 to C63;Carbonyl Compounds;Chemical Synthesis;Diacylglycerols;Esters;Lipids;Microscopy Reagents;Organic Building Blocks;Various Chemicals
• Mol File: 40290-32-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 64-66 °C
• Boiling Point: 620.8 °C at 760 mmHg
• Flash Point: 174.7 °C
• Appearance: /
• Density: 0.93 g/cm³
• Storage Temp.: −20°C
• PKA: 13.69±0.10(Predicted)
• BRN: 1809777
• CAS DataBase Reference: 1,2-DIPALMITOYL-RAC-GLYCEROL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIPALMITOYL-RAC-GLYCEROL(40290-32-2)
• EPA Substance Registry System: 1,2-DIPALMITOYL-RAC-GLYCEROL(40290-32-2)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 1
• Hazardous Substances Data: 40290-32-2(Hazardous Substances Data)

Usage

Description

1,2-Dipalmitoyl-rac-glycerol, also known as 1,2-dipalmitoyl-sn-glycerol, is a 1,2-diglyceride that is obtained by the formal acylation of positions 1 and 2 of glycerol by hexadecanoic (palmitic) acid. It is an analog of the protein kinase C (PKC)-activating second messenger diacylglycerol and acts as a weak activator of PKC.

Uses

Used in Pharmaceutical Industry:
1,2-Dipalmitoyl-rac-glycerol is used as a research compound for studying the role of diacylglycerol in cellular signaling and its interaction with protein kinase C (PKC). Its weak activation of PKC makes it a valuable tool in understanding the mechanisms of PKC activation and its implications in various cellular processes.
Used in Biochemical Research:
1,2-Dipalmitoyl-rac-glycerol is used as a reagent in biochemical research to investigate the function and regulation of PKC and other related signaling pathways. 1,2-DIPALMITOYL-RAC-GLYCEROL can help researchers gain insights into the molecular mechanisms underlying various diseases and conditions where PKC plays a crucial role.
Used in Drug Development:
1,2-Dipalmitoyl-rac-glycerol can be utilized in the development of novel therapeutic agents targeting PKC, which is involved in various cellular processes, including cell growth, differentiation, and apoptosis. By understanding the interactions between this compound and PKC, researchers can potentially develop new drugs that modulate PKC activity for the treatment of diseases where PKC dysregulation is a contributing factor.
Used in Cell Signaling Studies:
1,2-Dipalmitoyl-rac-glycerol is used as a tool in cell signaling studies to explore the role of diacylglycerol and its analogs in the activation of various signaling pathways. 1,2-DIPALMITOYL-RAC-GLYCEROL can help researchers identify potential targets for therapeutic intervention in diseases associated with aberrant cell signaling.

InChI:InChI=1/C35H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(37)39-32-33(31-36)40-35(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h33,36H,3-32H2,1-2H3