4032-80-8

Basic information

• Product Name: di-o-tolyl disulphide
• Synonyms: di-o-tolyl disulphide;1,1'-Dithiobis(2-methylbenzene);Bis(2-methylphenyl) persulfide;Di(o-tolyl) persulfide;Di-o-tolyl persulfide;BIS(2-METHYLPHENYL) DISULFIDE
• CAS NO: 4032-80-8
• Molecular Formula: C₁₄H₁₄S₂
• Molecular Weight: 246.39096
• EINECS: 223-715-1
• Mol File: 4032-80-8.mol
• Article Data: 94

Chemical Properties

• Boiling Point: 327.9°Cat760mmHg
• Flash Point: 162.9°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.000376mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: di-o-tolyl disulphide(CAS DataBase Reference)
• NIST Chemistry Reference: di-o-tolyl disulphide(4032-80-8)
• EPA Substance Registry System: di-o-tolyl disulphide(4032-80-8)

Safety Data

• Hazardous Substances Data: 4032-80-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 83, p. 1256, 1961 DOI: 10.1021/ja01466a060

InChI:InChI=1/C14H14S2/c1-11-7-3-5-9-13(11)15-16-14-10-6-4-8-12(14)2/h3-10H,1-2H3

Upstream product

• 38045-42-0 S-(2-methylphenyl) 2-methylbenzenesulfonothioate 
• 137-06-4 2-thiocresol 
• 133-59-5 Toluene-2-sulfonyl chloride 
• 932-31-0 ortho-tolylmagnesium bromide 
• 88-19-7 methyl 2-(aminosulfonyl)benzoate 
• 81994-64-1 2-[(2-methylphenyl)thio]pyridine 
• 63369-67-5 2-methylbenzenesulfinyl chloride 
• 88-20-0 o-toluenesulfonic acid 
• 2093-46-1 2-methylphenyl diazonium tetrafluoroborate 
• 594-42-3 chlorothio-trichloro-methane 
• 15046-75-0 sodium o-toluenesulfonate 
• 110-91-8 morpholine 
• 186098-94-2 S-(2-methylphenyl) 2-methylbenzenesulfinothioate 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 137-06-4 2-thiocresol 
• 24309-31-7 1-methyl-2-prop-2-enylsulfanylbenzene 
• 947735-31-1 C₂₂H₂₈S₂ 
• 14738-25-1 ethyl 2-<(2'-methylphenyl)sulfanyl>ethanoate 
• 1451371-39-3 2-(o-tolylthio)-1,4-dioxane 
• 1451371-47-3 2-(o-tolylthio)tetrahydrofuran 
• 1451371-50-8 (tert-butoxymethyl)(o-tolyl)sulfane 
• 1451371-58-6 ((2-methoxyethoxy)methyl)(o-tolyl)sulfane 
• 95493-62-2 S-(o-tolyl) 4-methylbenzenesulfonothioate 
• 69984-33-4 bis(o-methylphenylthio)methane 

Relevant articles and documents

Forging C?S(Se) Bonds by Nickel-catalyzed Decarbonylation of Carboxylic Acid and Cleavage of Aryl Dichalcogenides

A nickel-catalyzed decarbonylation of carboxylic acids cross-coupling protocol has been developed for the straightforward C?S(Se) bond formation. This reaction is promoted by a commercially-available, user-friendly, inexpensive, air and moisture-stable nickel precatalyst. Various carboxylic acids and a wide range of aryl dichalcogenide substrates were tolerated in this process which afforded products in good to excellent yields. In addition, the present reaction can be conducted on gram scale in good yield.

An unconventional sulfur-to-selenium-to-carbon radical transfer: Chemo-and regioselective cyclization of yne-ynamides

An uncommon sulfur → selenium → carbon radical transfer process is employed to develop an unprecedented selenyl radical-mediated regioselective cyclization of yne-tethered-ynamides. Density functional theory studies and HRMS experiments are used to establish a reactivity scale between thiyl and selenyl radicals. The unique features of this transformation include, (1) the chemoselective reactivity of RSe over RS, (2) regioselective RSe attack on alkyne over ynamide, (3) 5-exo-dig cyclization of yne-ynamide to unusual 4-selenyl-pyrroles, and (4) the green synthetic method. The reaction of methyldiselenide with yne-ynamides to methylselenopyrroles is also described.

Method for synthesizing symmetric disulfide compound by taking aryl hydrazine and S8 as raw materials

The invention relates to a method for synthesizing a symmetric disulfide compound by taking aryl hydrazine and S8 as raw materials, and belongs to the technical field of organic synthesis; the methodis characterized in that the aryl hydrazine compound and S8 are used as substrates to react in a reaction solvent under the promotion of alkali to generate the symmetric disulfide organic compound, the reaction gas atmosphere is air or oxygen, the reaction temperature is 40 DEG C-100 DEG C, and the reaction time is 4-24 hours. The synthesis steps are simple, the reaction conditions are mild, S8 which is widely distributed in nature, low in price and easy to obtain is used as a sulfur source, S-S bonds can be constructed only under the promotion of alkali without transition metal catalysis, theyield is as high as 95%, the applicable reaction substrate range is wide, the operation is simple and feasible, the synthesis cost is low, the environmental pollution is small, and a new thought is provided for the synthesis of the symmetric disulfide organic compound.