403483-56-7

Basic information

• Product Name: 2-Cyclohexen-1-one, 4,4,6-trimethyl-6-[3-oxo-5-[(tetrahydro-2H-pyran-2-yl)oxy]pentyl]-
• CAS NO: 403483-56-7
• Molecular Formula: C19H30O4
• Molecular Weight: 322.445
• Mol File: 403483-56-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-one, 4,4,6-trimethyl-6-[3-oxo-5-[(tetrahydro-2H-pyran-2-yl)oxy]pentyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 4,4,6-trimethyl-6-[3-oxo-5-[(tetrahydro-2H-pyran-2-yl)oxy]pentyl]-(403483-56-7)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 4,4,6-trimethyl-6-[3-oxo-5-[(tetrahydro-2H-pyran-2-yl)oxy]pentyl]-(403483-56-7)

Safety Data

• Hazardous Substances Data: 403483-56-7(Hazardous Substances Data)

Upstream product

• 403483-52-3 6-[(E)-3-(Dimethyl-phenyl-silanyl)-5-(tetrahydro-pyran-2-yloxy)-pent-2-enyl]-4,4,6-trimethyl-cyclohex-2-enone 
• 500591-01-5 Methanesulfonic acid (E)-3-(dimethyl-phenyl-silanyl)-5-(tetrahydro-pyran-2-yloxy)-pent-2-enyl ester 
• 403483-51-2 (2E)-1-iodo-3-(dimethylphenylsilyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]pentene 
• 403483-50-1 (2E)-3-(dimethylphenylsilyl)-5-[(tetrahydro-2H-pyran-2-yl)oxy]penten-1-ol 
• 13395-73-8 4,4,6-trimethylcyclohex-2-en-1-one 
• 51442-80-9 5-(tetrahydro-2H-pyran-2-yloxy)-2-pentyn-1-ol 
• 1073-13-8 4,4-dimethylcyclohexenone 
• 403483-54-5 6-{3-(dimethyl-phenyl-silanyl)-3-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-oxiranylmethyl}-4,4,6-trimethyl-cyclohex-2-enone 

Downstream Products

• 403483-57-8 6-(5-hydroxy-3-oxo-pentyl)-4,4,6-trimethyl-cyclohex-2-enone 

Relevant articles and documents

A novel extension of the Stork-Jung vinylsilane Robinson annelation procedure for the introduction of the cyclohexene of guanacastepene

A new annelation procedure has been developed in a model system to introduce the cyclohexene ring of guanacastepene. Cyclohexenone 16 is prepared by sequential methylation and alkylation with allylic iodide 15. One-pot epoxidation, protodesilylation and hydrolysis of the THP forms dione 19, which cyclizes with NaOMe to 24 in 57% overall yield. Reduction, Mitsunobu inversion, and selective oxidation of the primary alcohol forms model 29. Phenyldimethylsilyl allylic iodide 36 is easier to make and more stable than trimethylsilyl allylic iodide 6 used by Stork.