405090-30-4

Basic information

• Product Name: 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE
• Synonyms: 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE;CYCLOBUTANECARBONITRILE, 1-(4-FLUOROPHENYL)-
• CAS NO: 405090-30-4
• Molecular Formula: C11H10FN
• Molecular Weight: 175.21
• Mol File: 405090-30-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE(405090-30-4)
• EPA Substance Registry System: 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE(405090-30-4)

Safety Data

• Hazardous Substances Data: 405090-30-4(Hazardous Substances Data)

Usage

General Description

1-(4-fluorophenyl)cyclobutanecarbonitrile is a chemical compound with the molecular formula C11H8FN. It is a white to off-white crystalline solid that is insoluble in water and soluble in organic solvents. 1-(4-FLUOROPHENYL)CYCLOBUTANECARBONITRILE is used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and ability to introduce the 4-fluorophenyl and cyclobutane moieties into more complex molecules. It may also have potential applications in the development of new materials and as a research tool in the study of chemical reactions and organic synthesis. However, it is important to handle this compound with care and use appropriate safety precautions, as it may be hazardous if not handled properly.

Upstream product

• 459-22-3 4-fluorophenylacetonitrile 
• 109-70-6 1.3-chlorobromopropane 
• 109-64-8 1,3-dibromo-propane 

Relevant articles and documents

Synthesis method of arylcyclobutane compound

The present invention discloses a method for synthesizing an arylcyclobutane compound to 1eq phenylacetonitrile and 1.1eq 1-bromo-3-chloropropane as raw material, N,N- dimethylacetamide as a solvent, plus 2.5eq sodium hydride, under the protection of iner

Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same

The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017

Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R2, R4, R5, R6, R7, R8, R9, X, Z1, Z2, Z3, Z4 and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.