40642-43-1

Basic information

• Product Name: CIS-7-TETRADECENOL
• Synonyms: CIS-7-TETRADECENOL;(7Z)-7-Tetradecen-1-ol;(Z)7-Tetradecen-1-ol;7-Tetradecen-1-ol, (Z);cis-7-Tetradecen-1-ol;Z-7-Tetradecenol;(Z)-7-TDOL;Z-7-TDOL
• CAS NO: 40642-43-1
• Molecular Formula: C₁₄H₂₈O
• Molecular Weight: 212.37152
• Mol File: 40642-43-1.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 305.3°C at 760 mmHg
• Flash Point: 61 °C
• Appearance: /
• Density: 0.846g/cm³
• Vapor Pressure: 7.8E-05mmHg at 25°C
• Refractive Index: 1.458
• Storage Temp.: 2-8°C
• Solubility: Acetone, Chloroform, Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: CIS-7-TETRADECENOL(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-7-TETRADECENOL(40642-43-1)
• EPA Substance Registry System: CIS-7-TETRADECENOL(40642-43-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 40642-43-1(Hazardous Substances Data)

Usage

Description

CIS-7-TETRADECENOL, also known as cis-7-tetradecen-1-ol, is a naturally occurring organic compound that belongs to the class of alkenols. It is characterized by the presence of a double bond in its structure, which contributes to its unique chemical properties and potential applications. CIS-7-TETRADECENOL is derived from the fatty acid metabolism and is involved in various biological processes.

Uses

Used in Pharmaceutical Industry:
CIS-7-TETRADECENOL is used as an intermediate in the synthesis of (4E, 11Z)-Sphingadienine-C18-1-phosphate, which is a sphingoid base of sea cucumber cerebroside. CIS-7-TETRADECENOL has shown potential cytotoxicity activity against human colon cancer cells, making it a promising candidate for the development of novel anticancer drugs.
Used in Chemical Synthesis:
CIS-7-TETRADECENOL can be utilized as a key intermediate in the synthesis of various complex organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its unique structural features, including the presence of a double bond, make it a valuable building block for the development of new molecules with diverse biological activities.

InChI:InChI=1/C14H28O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h7-8,15H,2-6,9-14H2,1H3/b8-7-

Upstream product

• 70680-14-7 ethyl (Z)-tetradec-7-enoate 
• 111-71-7 heptanal 
• 76771-95-4 7-hydroxy-heptyl-triphenyl-phosphonium bromide 
• 37011-94-2 7-tetradecyne-1-ol 
• 16974-10-0 1-acetoxy-(Z)-7-tetradecene 
• 49592-98-5 (Z)-methyl tetradec-7-enoate 
• 629-05-0 n-octyne 
• 60579-52-4 1-chloro-1-boracycloheptane 
• 109537-09-9 (Z)-2-(tetradec-7-en-1-yloxy)tetrahydro-2H-pyran 
• 22054-13-3 7-hydroxyheptanal 
• 55367-56-1 n-heptylidene triphenylphosphorane 
• 37043-40-6 2-(tetradec-7-yn-1-yloxy)tetrahydro-2H-pyran 
• 53963-10-3 2-[(6-bromohexyl)oxy]tetrahydro-2H-pyran 
• 533-87-9 threo-9,10,16-trihydroxyhexadecanoic acid 

Downstream Products

• 16974-10-0 1-acetoxy-(Z)-7-tetradecene 
• 2430-95-7 (Z)-tetradec-7-enoic acid 
• 1352404-14-8 (7R,8S)-methyl 7,8-bis((S)-2-methoxy-2-phenylacetoxy)tetradecanoate 
• 1352404-40-0 (7S,8R)-methyl 7,8-bis((S)-2-methoxy-2-phenylacetoxy)tetradecanoate 
• 76963-23-0 3-oxo-(Z)-9-hexadecenal 
• 83005-39-4 sec-butyl (Z)-7-tetradecenoate 
• 592543-41-4 2-(4-methoxybenzyloxy)ethyl 2-deoxy-2-(2,2-difluorotetradecanamido)-4,6-O-isopropylidene-3-O-[(R)-3-[(Z)-tetradec-7-enyloxy]tetradecyl]-α-D-glycopyranoside 
• 592543-40-3 2-(4-methoxybenzyloxy)ethyl 2-deoxy-4,6-O-isopropylidene-3-O-[(R)-3-[(Z)-tetradec-7-enyloxy]tetradecyl]-2-trifluoroacetamido-α-D-glycopyranoside 
• 65128-96-3 (Z)-7-tetradecenal 

Relevant articles and documents

Method for synthesizing cis-7-tetradecenol acetate which is main component of sex pheromone of holcocerus vicarius walker

The invention discloses a method for synthesizing cis-7- tetradecenol acetate which is a main component of sex pheromone of holcocerus vicarius walker. The method includes (1), preparing (7-bromo-heptyl-1-)-2-tetrahydropyran ether; (2), preparing (7-bromo

Synthesis of highly enantioenriched hydroxy- and dihydroxy-fatty esters: Substrate precursors for cytochrome P450BioI

A series of highly enantioenriched hydroxy- and dihydroxy-fatty esters were required as part of our ongoing investigation into cytochrome P450 BioI. This mediates the biosynthesis of pimelic acid via C-C bond cleavage of long chain fatty acids within Bacillus subtilis. Herein we report the synthesis of various stereoisomers of methyl 7-hydroxytetradecanoate, methyl 8-hydroxytetradecanoate, and methyl 7,8-dihydroxytetradecanoate in highly enantioenriched form, using a combination of asymmetric synthesis and a preparative enantioselective HPLC is reported.

B-5354a, b and c, new sphingosine kinase inhibitors, produced by a marine bacterium; taxonomy, fermentation, isolation, physico-chemical properties and structure determination

In the course of our screening for inhibitors of sphingosine kinase, we found a series of active compounds in a culture broth of a novel marine bacterium, SANK 71896. The structures of the compounds, named B-5354a, b and c, were elucidated by a combination of spectroscopic analyses to be new esters of 4-amino-3-hydroxybenzoic acid with long-chain unsaturated alcohols. B-5354a, b and c inhibit sphingosine kinase activity with IC50 values of 21, 58 and 38 υM, respectively.