406479-01-4Relevant articles and documents
Conformationally restricted TRH analogues: Constraining the pyroglutamate region
Simpson, Jill C.,Ho, Chris,Berkley Shands,Gershengorn, Marvin C.,Marshall, Garland R.,Moeller, Kevin D.
, p. 291 - 302 (2007/10/03)
A modified synthetic route has been developed so that the steric size of constraints added to the pyroglutamate region of TRH (pGluHisProNH2) can be varied. Both an analogue with a smaller ethylene bridge and a larger, more flexible propane bri