40932-43-2

Basic information

• Product Name: 2-Chloro-3-methylaminopyridine
• Synonyms: 2-CHLORO-3-METHYLAMINOPYRIDINE;2-CHLORO-3-(AMINOMETHYL)PYRIDINE;2-CHLORO-3-METHYLAMINOPYRIDINE,=99%;2-Chloro-N-methylpyridin-3-amine;2-Chloro-3-methylaminepyridine;2-chloro-N-Methyl-3-PyridinaMine
• CAS NO: 40932-43-2
• Molecular Formula: C₆H₇ClN₂
• Molecular Weight: 142.59
• EINECS: 201-525-2
• Product Categories: pharmacetical;Pyridines
• Mol File: 40932-43-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 250.708 °C at 760 mmHg
• Flash Point: 105.425 °C
• Appearance: /
• Density: 1.25 g/cm³
• Vapor Pressure: 0.021mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-Chloro-3-methylaminopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-methylaminopyridine(40932-43-2)
• EPA Substance Registry System: 2-Chloro-3-methylaminopyridine(40932-43-2)

Safety Data

• Hazardous Substances Data: 40932-43-2(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-methylaminopyridine, also known as CMP, is a chemical compound with the molecular formula C6H6ClN2. It is a highly versatile building block used in the synthesis of pharmaceuticals and agrochemicals. CMP is widely employed in the pharmaceutical industry for the preparation of various drugs, including antihistamines, antifungal, and anti-inflammatory agents. It is also used as an intermediate in the manufacturing of pesticides and herbicides. CMP's unique structure and reactivity make it an important component in the synthesis of a wide range of valuable chemical compounds with diverse applications. However, it is important to handle CMP with care as it is a hazardous material and should only be used by trained professionals in appropriate laboratory settings.

InChI:InChI=1/C6H7ClN2/c1-8-5-3-2-4-9-6(5)7/h2-4,8H,1H3

Upstream product

• 6298-19-7 2-chloro-3-aminopyridine 
• 74-88-4 methyl iodide 
• 209798-48-1 tert-butyl N-(2-chloro-3-pyridinyl)carbamate 
• 100062-14-4 N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide 
• 106320-35-8 N-(2-chloro-[3]pyridyl)-N-methyl-toluene-4-sulfonamide 

Downstream Products

• 383901-46-0 1-[(2-chloro-3-pyridinyl)methylamino]-3-(phenylmethoxy)-2-propanol 
• 1225208-05-8 4-Hydroxy-1-methyl-3-(2-trifluoromethylphenyl)-1H-[1,5]naphthyridin-2-one 
• 1225208-28-5 methyl 3-{methyl-[2-(2-trifluormethyl-phenyl)-acetyl]-amino}-pyridine-2-carboxylate 
• 142670-95-9 N-Benzyl-3-(4-methoxyphenyl)-2-diphenylphosphinoyl-1H-pyrido<2,3-b><1,4>thiazine 
• 142670-94-8 N-Benzyl-3-(4-chlorophenyl)-2-diphenylphosphinoyl-1H-pyrido<2,3-b><1,4>thiazine 
• 142670-96-0 N-Benzyl-3-(2-furyl)-2-diphenylphosphinoyl-1H-pyrido<2,3-b><1,4>thiazine 
• 142670-91-5 N-Methyl-3-phenyl-2-diphenylphosphinoyl-1H-pyrido<2,3-b><1,4>thiazine 
• 142670-88-0 2-(N-Methyl-N-diphenylphosphinoylmethylamino)-2-chloropyridine 
• 623912-25-4 3-benzyloxymethyl-1-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine 
• 56291-51-1 2-amino-3-methylaminopyridine 

Relevant articles and documents

Development of P- And N-Chirogenic Ligands Based on Chiral Induction from a Phosphorus Donor to a Nitrogen Donor in Palladium Complexes

We herein designed and synthesized amino-phosphine ligands 1a-c, which bear a P-chirogenic group, (R)-PtBuMe, and an N-group (NHR) on the pyridylene backbone, as a novel class of chiral ligands possessing chirogenic donors. Ligand 1a (R = Me) stereoselectively coordinated with PdCl2 to predominantly afford the P- and N-chirogenic metal complex 4a having an RN,SP configuration. In contrast, ligands 1b (R = iPr) and 1c (R = tBu) produced a mixture of diastereomers derived from two possible N-centered configurations. In complex 4a, the N-centered configuration was efficiently controlled by the P-chirogenic center via through-space attractive interactions between P-tBu and N-Me. Buried volume analysis indicated that this novel ligand creates a unique C1-symmetric chiral environment derived from both steric and electronic asymmetry.

Novel Iridium complex and organic light emitting device comprising the same

The present invention provides a novel iridium complex compound and an organic light emitting device using the same. The iridium complex compound represented by chemical formula 1 can be used as a material of an organic material layer of the organic light emitting device, can be used in a solution process, and can improve efficiency in the organic light emitting device.COPYRIGHT KIPO 2020

HYDROXYL PURINE COMPOUNDS AND USE THEREOF

Disclosed are a series of hydroxyl purine compounds and the use thereof as PDE2 or TNFα inhibitors, in particular, the compounds as shown in formula (I), or tautomers thereof or pharmaceutically acceptable salts thereof.