41019-43-6

Basic information

• Product Name: 5-(2-CHLOROPHENYL)-2-FUROIC ACID
• Synonyms: SALOR-INT L480908-1EA;TIMTEC-BB SBB009790;RARECHEM AL BE 0772;ART-CHEM-BB B025310;ASISCHEM T31124;CHEMBRDG-BB 4013146;AKOS BAR-0172;5-(2-CHLOROPHENYL)-2-FUROIC ACID
• CAS NO: 41019-43-6
• Molecular Formula: C₁₁H₇ClO₃
• Molecular Weight: 222.62
• Mol File: 41019-43-6.mol
• Article Data: 22

Chemical Properties

• Melting Point: 167-168 °C(Solv: dichloromethane (75-09-2))
• Boiling Point: 376.3 °C at 760 mmHg
• Flash Point: 181.4 °C
• Appearance: /
• Density: 1.374 g/cm³
• Vapor Pressure: 2.49E-06mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: 2-8°C
• PKA: 2.99±0.10(Predicted)
• CAS DataBase Reference: 5-(2-CHLOROPHENYL)-2-FUROIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-CHLOROPHENYL)-2-FUROIC ACID(41019-43-6)
• EPA Substance Registry System: 5-(2-CHLOROPHENYL)-2-FUROIC ACID(41019-43-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 41019-43-6(Hazardous Substances Data)

Usage

General Description

5-(2-Chlorophenyl)-2-furoic acid is a chemical compound with the molecular formula C11H7ClO3. It is a derivative of furoic acid, which is a heterocyclic compound containing a five-membered ring with an oxygen atom. The presence of a chlorophenyl group in the molecule indicates the substitution of a phenyl ring with a chlorine atom. 5-(2-CHLOROPHENYL)-2-FUROIC ACID has potential applications in the pharmaceutical and agrochemical industries due to its structural properties. It may be used as a building block in the synthesis of various organic compounds and can also have biological activities that make it useful for research and development purposes.

InChI:InChI=1/C11H7ClO3/c12-8-4-2-1-3-7(8)9-5-6-10(15-9)11(13)14/h1-6H,(H,13,14)

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 41019-38-9 5-(2-chlorophenyl)furan-2-carboxylic acid methyl ester 
• 88-14-2 2-furanoic acid 
• 95-51-2 o-chloroaniline 

Downstream Products

• 627042-89-1 6-[5-(2-chlorophenyl)furan-2-yl]-3-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 
• 34035-04-6 5-(2-chlorophenyl)furan-2-carbaldehyde 
• 1410785-85-1 C₂₁H₁₆BrClN₂O₃ 
• 1410785-82-8 C₂₀H₁₄BrClN₂O₃ 
• 1410785-72-6 4-bromobenzaldehyde (5-(2-chlorophenyl)-2-furoyl)hydrazone 
• 1410785-73-7 C₁₈H₁₀BrClN₂O₂ 
• 1057658-84-0 N-(4-bromobenzoyl)-N′-[5-(2′-chlorophenyl)-2-furoyl]hydrazine 

Relevant articles and documents

Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity

NMDA receptors mediate glutamatergic neurotransmission and are therapeutic targets due to their involvement in a variety of psychiatric and neurological disorders. Here, we describe the design and synthesis of a series of (R)-3-(5-furanyl)carboxamido-2-am

Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships

Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanamide de

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

The synthesis and biological evaluation as potential urotensin-II receptor antagonists of a series of 5-arylfuran-2-carboxamide derivatives 1, bearing a 4-(3-chloro-4-(piperidin-4-yloxy)benzyl)piperazin-1-yl group, are described. The results of a systemat