41046-70-2

Basic information

• Product Name: 2-Iodo-5-Methoxyphenol
• Synonyms: 2-Iodo-5-Methoxyphenol;3-Methoxy-6-iodophenol
• CAS NO: 41046-70-2
• Molecular Formula: C₇H₇IO₂
• Molecular Weight: 250.03375
• Mol File: 41046-70-2.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Iodo-5-Methoxyphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodo-5-Methoxyphenol(41046-70-2)
• EPA Substance Registry System: 2-Iodo-5-Methoxyphenol(41046-70-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 41046-70-2(Hazardous Substances Data)

Usage

General Description

2-Iodo-5-Methoxyphenol, also known as iodoanisole, is a chemical compound with the molecular formula C7H7IO2. It is a derivative of phenol and is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It is a white to off-white crystalline solid that is soluble in organic solvents such as acetone, ether, and chloroform. 2-Iodo-5-Methoxyphenol is commonly used in organic and medicinal chemistry as a building block for the preparation of various compounds, and its properties make it suitable for applications in the pharmaceutical industry. It is also utilized in the synthesis of dyes and pigments. This chemical compound is classified as a hazardous substance and should be handled and stored according to appropriate safety guidelines.

Upstream product

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Downstream Products

• 81245-38-7 1-iodo-4-methoxy-2-(methoxymethoxy)-benzene 
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• 1259295-19-6 5-methoxy-2-(2-phenylethynyl)phenol 
• 1319803-89-8 2-(3-N,N-dibenzyl-4-methoxyphenyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan 
• 1319803-90-1 6-methoxy-2-(N-methyl-5-indolyl)-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan 
• 1319803-91-2 2-(4-benzyloxyphenyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan 
• 1319803-94-5 2-(4-hydroxyphenyl)-6-methoxy-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan 
• 905752-26-3 2-bromo-6-methoxy-3-(3,4,5-trimethoxybenzoyl)-benzo[b]furan 
• 1393671-15-2 (+)-1-iodo-4-methoxy-2-{[(1R)-1-methylprop-2-yn-1-yl]oxy}benzene 
• 1393671-17-4 (+)-[(3R)-3-(2-iodo-5-methoxyphenoxy)but-1-yn-1-yl][tris(1-methylethyl)]silane 
• 1393671-18-5 (+)-[(3R)-3-(2-{[4-methoxy-2-({(1R)-1-methyl-3-[tris(1-methylethyl)silyl]prop-2-yn-1-yl}oxy)phenyl]ethynyl}phenoxy)but-1-yn-1-yl][tris(1-methylethyl)]silane 
• 1393671-20-9 (+)-4-methoxy-2-{[(1R)-1-methylprop-2-yn-1-yl]oxy}-1-[(2-{[(1R)-1-methylprop-2-yn-1-yl]oxy}phenyl)ethynyl]benzene 

Relevant articles and documents

SULFINIC ACID COMPOUNDS AS FREE FATTY ACID RECEPTOR AGONISTS

The present invention relates to certain compounds, their use in therapy, as well as to pharmaceutical compositions including said compounds. Specifically, the invention relates to certain compounds and pharmaceutical compositions including these compounds for the treatment of metabolic disorders including, for example, diabetes, obesity, metabolic syndrome, fatty liver disease, and bone disorders.

Synthesis of 2-arylbenzofuran-3-carbaldehydes: via an organocatalytic [3+2] annulation/oxidative aromatization reaction

A novel organocatalytic [3+2] annulation/oxidative aromatization reaction of enals with 2-halophenols or β-naphthols is reported. This process enables chemo- and regioselective access to 2-arylbenzofuran-3-carbaldehydes without the use of transition metals or strong oxidants. Preliminary mechanistic studies reveal that an unprecedented, organocatalytic, direct α-arylation pathway is involved.

Synthesis of 8-azaprotosappanin A derivatives via intramolecular palladium-catalyzed ortho C-H activation/C-C cyclization and their antibacterial activity

A novel synthetic protocol for the construction of eight-membered heterocycles by intramolecular palladium-catalyzed ortho C-H activation/C-C cyclization was proposed. With protosappanin A as the lead compound, 25 derivatives of 8-azaprotosappanin A were prepared in good yields by this protocol. Besides, a plausible reaction mechanism of the intramolecular cyclization was proposed. This strategy could be widely used in the synthesis of some natural products and drugs with large heterocycles due to the fast reaction rate and the mild conditions. In vitro antimicrobial activities of the synthesized compounds were assessed against the strains of Gram-positive bacteria and linezolid and ciprofloxacin were selected as the standard drugs. Some of the synthesized compounds were found to have excellent antibacterial activities.