4105-92-4

Basic information

• Product Name: Triethyl 1,3,5-benzenetricarboxylate
• Synonyms: 1,3,5-Benzenetricarboxylic acid, triethyl ester;Triethyl trimesate;BENZENE-1,3,5-TRICARBOXYLIC ACID TRIETHYL ESTER;1,3,5-TRICARBOETHOXYBENZENE;TMSSE;TRIMESIC ACID TRIETHYL ESTER;TRIETHYL BENZENE-1,3,5-TRICARBOXYLATE;TRIETHYL 1,3,5-BENZENETRICARBOXYLATE
• CAS NO: 4105-92-4
• Molecular Formula: C₁₅H₁₈O₆
• Molecular Weight: 294.3
• Product Categories: C12 to C63;Carbonyl Compounds;Esters
• Mol File: 4105-92-4.mol
• Article Data: 61

Chemical Properties

• Melting Point: 134-139 °C(lit.)
• Boiling Point: 385.9°C at 760 mmHg
• Flash Point: 168.4°C
• Appearance: /
• Density: 1.164g/cm³
• Vapor Pressure: 3.68E-06mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Triethyl 1,3,5-benzenetricarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Triethyl 1,3,5-benzenetricarboxylate(4105-92-4)
• EPA Substance Registry System: Triethyl 1,3,5-benzenetricarboxylate(4105-92-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 4105-92-4(Hazardous Substances Data)

Usage

General Description

Triethyl 1,3,5-benzenetricarboxylate is a chemical compound with the formula C16H20O6. It is a colorless liquid with a fruity odor and is commonly used as a fragrance ingredient in various consumer products such as perfumes, colognes, and cosmetics. Triethyl 1,3,5-benzenetricarboxylate is also used as a plasticizer in the production of cellulose acetate films and in the manufacture of resins and polymers. Additionally, it has applications in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Triethyl 1,3,5-benzenetricarboxylate is considered to have low toxicity and is generally safe for use in the specified applications with proper handling and storage.

InChI:InChI=1/C15H18O6/c1-4-19-13(16)10-7-11(14(17)20-5-2)9-12(8-10)15(18)21-6-3/h7-9H,4-6H2,1-3H3

Upstream product

• 60-29-7 diethyl ether 
• 64-17-5 ethanol 
• 917-58-8 potassium ethoxide 
• 141-78-6 ethyl acetate 
• 109-94-4 formic acid ethyl ester 
• 5941-55-9 ethyl 3-ethoxyacrylate 
• 141-52-6 sodium ethanolate 
• 609-08-5 Diethyl methylmalonate 
• 68-12-2 N,N-dimethyl-formamide 
• 927-80-0 1-ethoxyacetylene 
• 623-47-2 propynoic acid ethyl ester 
• 58-61-7 adenosine 
• 34780-29-5 3-oxo-propionic acid ethyl ester 
• 7664-41-7 ammonia 

Downstream Products

• 51062-63-6 C₉₃H₁₂₆O₆ 
• 181425-91-2 diethyl 5-(hydroxymethyl)isophthalate 
• 250608-55-0 5-hydrazinocarbonyl-isophthalic acid diethyl ester 
• 5962-82-3 cis,cis-1,3,5-tris(hydroxymethyl)cyclohexane 
• 16526-68-4 cis-1,3,5-cyclohexane tricarboxylic acid 
• 56025-65-1 1,3,5-tris-bromomethyl-cyclohexane 
• 146669-14-9 1,3,5-benzene tricarboxylic acid tris-N-(2-aminoethyl)amide 
• 124680-84-8 2-nitro-1,3,5-tris(bromomethyl)benzene 
• 1610009-70-5 C₂₁H₃₂O₈ 
• 1610009-69-2 C₃₁H₄₈O₁₄ 
• 3163-76-6 benzene-1,3,5-trialdehyde 
• 950608-82-9 5-(5,5-Dimethyl-[1,3]dioxan-2-yl)-benzene-1,3-dicarbaldehyde 
• 28084-34-6 cis,cis-triethyl 1,3,5-cyclohexanetricarboxylate 
• 36997-31-6 benzene-1,3,5-tricarboxylic acid trihydrazide 

Relevant articles and documents

REACTION OF NUCLEOBASES WITH α-ACETYLENIC ESTERS, POTENTIALLY USEFULL FOR CHEMICAL MODIFICATION OF NUCLEIC ACIDS

The NH2 group and the adjacent ring nitrogen of adenosine and cytidine react with α-acetylenic esters by addition across the triple bond and formation of a lactam with the ester group.

Understanding the Incorporation and Release of Salicylic Acid in Metal-Organic Frameworks for Topical Administration

Although metal-organic frameworks (MOFs) have been widely demonstrated to be great candidates for drug delivery applications, they have been mainly proposed for the intravenous route. Here, eight highly porous benchmarked MOFs, with different topologies a

Cyclotrimerization of alkynes catalyzed by a self-supported cyclic tri-nuclear nickel(0) complex with α-diimine ligands

A cyclic tri-nuclear α-diimine nickel(0) complex [{Ni(μ-LMe-2,4)}3] (2) was synthesized from a “pre-organized”, trimerized trigonal LNiBr2-type precursor [Ni3(μ2-Br)3(μ3-Br)2(LMe-2,4)3]·Br (1; LMe-2,4 = [(2,4-Me2C6H3)NC(Me)]2). In complex 2, the α-diimine ligands not only exhibit the normal N,N′-chelating mode, but they also act as bridges between the Ni atoms through an unusual π-coordination of a C═N bond to Ni. Complex 2 is able to catalyze the cyclotrimerization of alkynes to form substituted benzenes in good yield and regio-selectivity for the 1,3,5-isomers, which is found to vary with the nature of the alkyne employed. This complex represents a convenient self-supported nickel(0) catalyst with no need for additional ligands and reducing agent.

Cyclotrimerization of phenylacetylene catalyzed by a cobalt half-sandwich complex embedded in an engineered variant of transmembrane protein FhuA

An (η5-cyclopentadienyl)cobalt(i) complex was covalently incorporated into an engineered variant of the transmembrane protein ferric hydroxamate uptake protein component: A, FhuA ΔCVFtev, using a thiol-ene reaction. A CD spectrum shows the structural integrity of the biohybrid catalyst. MALDI-TOF of the segment containing the anchoring site for the cobalt complex Cys545 confirmed successful conjugation. This biohybrid catalyst catalyzed the cyclotrimerization of phenylacetylene to give a mixture of regioisomeric 1,2,4- and 1,3,5-triphenylbenzene in aqueous medium.