4111-09-5Relevant articles and documents
A new (R)-hydroxynitrile lyase from Prunus mume: Asymmetric synthesis of cyanohydrins
Nanda, Samik,Kato, Yasuo,Asano, Yasuhisa
, p. 10908 - 10916 (2007/10/03)
A new hydroxynitrile lyase (HNL) was isolated from the seed of Japanese apricot (Prunus mume). The enzyme has similar properties with HNL isolated from other Prunus species and is FAD containing enzyme. It accepts a large number of unnatural substrates (benzaldehyde and its variant) for the addition of HCN to produce the corresponding cyanohydrins in excellent optical and chemical yields. A new HPLC based enantioselective assay technique was developed for the enzyme, which promotes the addition of KCN to benzaldehyde in a buffered solution (pH=4.5).
Trimethylsilyl bis(fluorosulfonyl)imide: An efficient catalyst for the addition of trimethylsilyl cyanide to carbonyl compounds
Kaur, Harpinder,Kaur, Gurmeet,Trehan, Sanjay
, p. 1925 - 1929 (2007/10/03)
In the presence of 1 mol% of trimethylsilyl bis(fluorosulfonyl)imide, trimethylsilyl cyanide adds efficiently to carbonyl compounds. The catalyst has been found to be more active than trimethylsilyl triflate for the above reaction.
ONE-STEP REMOTE OXIDATIVE CYANATION OF KETONES AND ALDEHYDES
Troyanskii, E. I.,Mizintsev, V. V.,Molokanov, A. N.,Ogibin, Yu. N.,Nikishin, G. I.
, p. 2499 - 2506 (2007/10/02)
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