41139-95-1 Usage
General Description
2-[(4-aminophenyl)amino]benzoic acid, also known as 4-Aminosalicylic acid or PAS, is an aromatic amine compound with the chemical formula C13H11N3O3. It is commonly used in the treatment of tuberculosis and as a diagnostic tool for assessing liver function. 4-Aminosalicylic acid works by inhibiting the growth of tuberculosis bacteria in the body, making it an important component of combination therapy for the disease. In addition, it is sometimes used in conjunction with other medications to treat certain types of inflammatory bowel disease, such as ulcerative colitis. 2-[(4-aminophenyl)amino]benzoic acid is typically administered orally in the form of a tablet or capsule and may have potential side effects, including gastrointestinal disturbances and allergic reactions. Overall, 4-Aminosalicylic acid plays a crucial role in the management of tuberculosis and related conditions, making it an important chemical in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 41139-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,3 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 41139-95:
(7*4)+(6*1)+(5*1)+(4*3)+(3*9)+(2*9)+(1*5)=101
101 % 10 = 1
So 41139-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H12N2O2/c14-9-5-7-10(8-6-9)15-12-4-2-1-3-11(12)13(16)17/h1-8,15H,14H2,(H,16,17)
41139-95-1Relevant articles and documents
A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site
Mamais, Michael,Degli Esposti, Alessandra,Kouloumoundra, Virginia,Gustavsson, Thomas,Monti, Filippo,Venturini, Alessandro,Chrysina, Evangelia D.,Markovitsi, Dimitra,Gimisis, Thanasis
supporting information, p. 8800 - 8805 (2017/07/11)
The design and synthesis of a glucose-based acridone derivative (GLAC), a potent inhibitor of glycogen phosphorylase (GP) are described. GLAC is the first inhibitor of glycogen phosphorylase, the electronic absorption properties of which are clearly distinguishable from those of the enzyme. This allows probing subtle interactions in the catalytic site. The GLAC absorption spectra, associated with X-ray crystallography and quantum chemistry calculations, reveal that part of the catalytic site of GP behaves as a highly basic environment in which GLAC exists as a bis-anion. This is explained by water-bridged hydrogen-bonding interactions with specific catalytic site residues.
Synthesis of N-phenylanthranilic acids using water as solvent
Pellon,Carrasco,Rodes
, p. 1447 - 1453 (2007/10/02)
A study of some parameters which influence the Ullmann-Goldberg condensation for the synthesis of N-phenylanthranilic acids was done, showing that these acids can be obtained efficiently using water as solvent.
Binding of N-phenylanthranilic acid derivatives to bovine serum albumin
Sharples
, p. 681 - 683 (2007/10/02)
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