41144-46-1

Basic information

• Product Name: 3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE
• Synonyms: 3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE;3-(tert-Butyl)-6-chloropyridazine
• CAS NO: 41144-46-1
• Molecular Formula: C8H11ClN2
• Molecular Weight: 170.64
• Mol File: 41144-46-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 270 °C at 760 mmHg
• Flash Point: 143.1 °C
• Appearance: /
• Density: 1.104 g/cm³
• PKA: 1.28±0.10(Predicted)
• CAS DataBase Reference: 3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE(41144-46-1)
• EPA Substance Registry System: 3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE(41144-46-1)

Safety Data

• Hazardous Substances Data: 41144-46-1(Hazardous Substances Data)

Usage

General Description

3-CHLORO-6-(1,1-DIMETHYLETHYL)-PYRIDAZINE is a chemical compound with the molecular formula C8H11ClN2. It is a yellow to brown liquid that is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also known by its CAS number 57260-71-6 and has a molecular weight of 174.64 g/mol. The compound is classified as a chloroalkylpyridazine and has potential applications in the development of new drugs and agrochemical products. However, it should be handled and stored with caution due to its potential hazards and risks to human health and the environment.

Upstream product

• 75-97-8 3,3-dimethyl-butan-2-one 
• 147849-82-9 6-tert-Butyl-3(2H)-pyridazinone 

Downstream Products

• 1616379-00-0 4-(benzyloxy)-6-tert-butyl-3-methoxypyridazine 

Relevant articles and documents

Bulk Inclusions of Double Pyridazine Molecular Rotors in Hexagonal Tris(o-phenylene)cyclotriphosphazene

A new generation of double pyridazine molecular rotors differing in intramolecular dipole-dipole spacing was synthesized. All rotor molecules formed bulk inclusions in a tris(o-phenylenedioxy)cyclotriphosphazene (TPP) host. Results of dielectric spectroscopy were fitted to a pair of nine-state models that accounted for interactions of neighboring dipoles at either an aligned or opposed possible orientation of the local threefold dipole rotation potentials within a channel of the TPP host. The results indicate dipole-dipole interaction strengths at the 100 to 200 K scale that lead dipoles to preferentially populate a subset of low-energy configurations. They also reveal that pyridazines with ethynyl substituents in 3- and 6-positions have slightly higher rotational barriers (3.2-3.5 kcal/mol) than those carrying one ethynyl and one tert-butyl group (1.9-3.0 kcal/mol). Upon cooling, these barriers reduce the rate of thermal transitions between the potential wells so much that the inclusions cannot achieve ordered dipolar ground states.