41150-48-5

Basic information

• Product Name: 4'-(4-Chlorophenoxy)acetophenone
• Synonyms: 1-acetyl-4-(4-chlorophenoxy)-benzene;Ethanone, 1-[4-(4-chlorophenoxy)phenyl]-;JR-6486, 1-(4-(4-Chlorophenoxy)phenyl)ethanone, 97%
• CAS NO: 41150-48-5
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.69
• Mol File: 41150-48-5.mol
• Article Data: 21

Chemical Properties

• Melting Point: 59～61℃C
• Appearance: /
• CAS DataBase Reference: 4'-(4-Chlorophenoxy)acetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-(4-Chlorophenoxy)acetophenone(41150-48-5)
• EPA Substance Registry System: 4'-(4-Chlorophenoxy)acetophenone(41150-48-5)

Safety Data

• Hazardous Substances Data: 41150-48-5(Hazardous Substances Data)

Usage

General Description

4'-(4-Chlorophenoxy)acetophenone is an organic compound with the chemical formula C14H11ClO2. It is a yellow crystalline solid that is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. This chemical is also used as a reagent in organic synthesis and as a building block in the production of various aromatic chemicals. It is important to handle 4'-(4-Chlorophenoxy)acetophenone with caution as it can be harmful if ingested or inhaled, and can cause irritation to the skin and eyes upon contact.

Upstream product

• 99-90-1 para-bromoacetophenone 
• 1193-00-6 sodium 4-chlorophenolate 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 403-41-8 1-(4-Fluorophenyl)ethanol 
• 106-48-9 4-chloro-phenol 
• 85014-03-5 (4-chlorophenoxymethyl)-(4-fluorophenyl)-ketone 
• 86-55-5 1-naphthalenecarboxylic acid 
• 13329-40-3 4-Iodoacetophenone 
• 30427-95-3 1-bromo-4-(4-chlorophenoxy)benzene 
• 75-36-5 acetyl chloride 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 7005-72-3 4-chlorodiphenyl ether 

Downstream Products

• 21120-67-2 4-(4'-chlorophenoxy)-benzoic acid 
• 58727-42-7 3-p-(p-chlorophenoxy)-phenyl-3-hydroxybutyric acid ethyl ester 
• 13221-80-2 2-chloro-1-[4-(4-chlorophenoxy)phenyl]ethanone 
• 1612765-04-4 1-chloro-2-[4-(4-chlorophenoxy)phenyl]pent-3-yn-2-ol 
• 1612764-98-3 1-(1,2,4-triazole)-2-[4-(4-chlorophenoxy)phenyl]pent-3-yn-2-ol 
• 1609174-07-3 N-(2-butoxy-4-(3-(diethylamino)propoxy)phenyl)-3-(4-(4-chlorophenoxy)phenyl)-1-methyl-1H-pyrazole-5-carboxamide 
• 1609174-08-4 N-(2-butoxy-4-(3-(diethylamino)propoxy)phenyl)-3-(4-(4-chlorophenoxy)phenyl)-1H-pyrazole-5-carboxamide 
• 84447-83-6 α-bromo-4-(4-chlorophenoxy)acetophenone 
• 1609174-28-8 ethyl 3-(4-(4-chlorophenoxy)phenyl)isoxazole-5-carboxylate 
• 1609173-94-5 ethyl 3-(4-(4-chlorophenoxy)phenyl)-1H-pyrazole-5-carboxylate 
• 1609174-09-5 N-(2-butoxy-4-(3-(diethylamino)propoxy)phenyl)-3-(4-(4-chlorophenoxy)phenyl)isoxazole-5-carboxamide 
• 1431875-89-6 2-(4-(4-chlorophenoxy)phenyl)-6-fluoroquinoline-4-carboxylic acid 
• 93496-94-7 2-[4-(4-Chloro-phenoxy)-benzyloxy]-3,3,3-trifluoro-2-methyl-propionic acid 
• 21120-74-1 methyl 4-(4-chlorophenoxy)benzoate 

Relevant articles and documents

Preparation method of diaryl ether compound

The invention relates to a preparation method of a diaryl ether compound. Particularly, under catalysis of chitosan supported cuprous oxide, an arylation reaction used for phenols is achieved, the corresponding diaryl ether compound is obtained, the technological condition is simple, the yield is good, operability is high, and wide functional group durability is achieved.

Exploring Tandem Ruthenium-Catalyzed Hydrogen Transfer and SNAr Chemistry

A hydrogen-transfer strategy for the catalytic functionalization of benzylic alcohols via electronic arene activation, accessing a diverse range of bespoke diaryl ethers and aryl amines in excellent isolated yields (38 examples, 70% average yield), is reported. Taking advantage of the hydrogen-transfer approach, the oxidation level of the functionalized products can be selected by judicious choice of simple and inexpensive additives.

Novel heteroarylcarboxamide derivative or pharmacutically acceptable salt thereof, process for the preparation thereof and pharmaceutical composition for prevention or treatment of RAGE receptor related diseases containing the same as an active ingredient

The present invention refers to novel heterocyclic biting Carbox probably the id derivative acceptable salt, and manufacturing method thereof including RAGE associated active acetylcholinesterase receptor or pharmaceutical composition for preventing or treating disease is directed to. Heterocycle by the present invention a derivative biting Carbox probably the id RAGE receptor antagonism in by, nerve cells with the beta loss oh with wheat id RAGE conjunction with receptor, inhibiting moving into brain, the resulting beta Amyloid plaque formed 21 is known to effectively inhibit generation.. Furthermore, memory a chemicals that are important in the acetylcholine for decomposing an aromatic thus inhibiting acetylcholine s reel sacrifice , RAGE disease associated active acetylcholinesterase receptor or Alzheimer's disease, cerebrovascular dementia, dementia due to damage bean curd, multi blockade dementia, Alzheimer's disease or the like dementia alcoholic or mixed dementia multi blockade and including dementia, pick (pick) bottle, a smartcrew [...] -Jakob (Creutzfeldt-jakob) bottle, that thyroid gland symptoms , bean curd a blade Parkinson (Parkinson) bottle, Huntington's disease (Huntington) which is useful in preventing or treating, can be used.