41252-98-6

Basic information

• Product Name: 2-IODO-6-NITROTOLUENE
• Synonyms: 2-IODO-6-NITROTOLUENE;5-IODO-6-METHYL-1-NITROBENZENE
• CAS NO: 41252-98-6
• Molecular Formula: C₇H₆INO₂
• Molecular Weight: 263.03
• Mol File: 41252-98-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 288.91°C at 760 mmHg
• Flash Point: 128.528°C
• Appearance: /
• Density: 1.884g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.644
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-IODO-6-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-6-NITROTOLUENE(41252-98-6)
• EPA Substance Registry System: 2-IODO-6-NITROTOLUENE(41252-98-6)

Safety Data

• Hazardous Substances Data: 41252-98-6(Hazardous Substances Data)

Usage

General Description

2-IODO-6-NITROTOLUENE is a chemical compound with the molecular formula C7H6INO2. It is a halogenated aromatic compound with a nitro group attached to the benzene ring. This chemical is primarily used in the synthesis of dyes, pigments, and pharmaceuticals. It is also used as an intermediate in the production of various organic compounds. 2-IODO-6-NITROTOLUENE is considered to be a hazardous substance and must be handled and stored with care due to its flammability and potential health hazards.

InChI:InChI=1/C7H6INO2/c1-5-6(8)3-2-4-7(5)9(10)11/h2-4H,1H3

Upstream product

• 603-83-8 3-nitro-o-tolylamine 
• 606-20-2 2,6-dinitrotoluene 
• 88-72-2 1-methyl-2-nitrobenzene 

Downstream Products

• 86560-87-4 2,2'-diamino-6,6'-dimethylbiphenyl 
• 3685-05-0 (S)-6,6'-dimethyl-2,2'-diaminobiphenyl 
• 3685-05-0 (Ra)-6,6'-dimethyl-1,1'-biphenyl-2,2'-diamine 
• 23876-15-5 2-(3-nitro-2-methylphenyl)acetic acid 
• 81038-38-2 4-iodo-1H-indole 
• 939759-03-2 4-iodoindoline 
• 88-72-2 1-methyl-2-nitrobenzene 
• 31354-19-5 2,2'-dimethyl-3,3'-dinitrobiphenyl 
• 1254709-93-7 methyl 2-(3-methyl-4-nitrophenyl)thiophene-3-carboxylate 
• 860190-34-7 (2-iodo-6-nitro-phenyl)-pyruvic acid 
• 1072801-03-6 4-[4-(chloromethyl)benzyl]-2-methyl-1-nitrobenzene 

Relevant articles and documents

N-Iodosuccinimide (NIS) in Direct Aromatic Iodination

N-Iodosuccinimide (NIS) in pure trifluoroacetic acid (TFA) offers a time-efficient and general method for the iodination of a wide range of mono- and disubstituted benzenes at room temperature, as demonstrated in this paper. The starting materials were generally converted into mono-iodinated products in less than 16 hours at room temperature, without byproducts. A few deactivated substrates needed addition of sulfuric acid to increase the reaction rate. Another exception was methoxybenzenes that preferentially were iodinated by NIS in acetonitrile with only catalytic amounts of TFA.

Synthetic studies toward penitrem E: Enantiocontrolled construction of B-E rings

Enantiocontrolled construction of B-E rings of penitrem E was accomplished from 4-iodoindole in 13 steps with an overall yield of 1.7%. Diastereoselective Tf2NH-catalyzed (2+2)-cycloaddition between silyl enol ether and methyl acrylate furnishe

Novel biphenyl organocatalysts for iminium ion-catalyzed asymmetric epoxidation

Two novel chiral biphenyl iminium salts derived from L-acetonamine, containing electron-withdrawing 3,30-substituents on the biphenyl unit, have been prepared and tested as asymmetric catalysts for epoxidation of prochiral alkenes. The results are compared with those achieved using the corresponding unsubstituted system.