41321-75-9

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methyl-
• CAS NO: 41321-75-9
• Molecular Formula: C11H9BrO2
• Molecular Weight: 253.095
• Mol File: 41321-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methyl-(41321-75-9)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methyl-(41321-75-9)

Safety Data

• Hazardous Substances Data: 41321-75-9(Hazardous Substances Data)

Upstream product

• 13176-46-0 4-bromoethyl acetoacetate 
• 108-39-4 3-methyl-phenol 

Downstream Products

• 883222-49-9 4-(2,4-diacetyl-5-hydroxy-phenoxymethyl)-7-methyl-chromen-2-one 
• 105916-65-2 7-methyl-4-(N-morpholinomethyl)coumarin 
• 98317-61-4 4-Aminomethyl-7-methyl-chromen-2-one; hydrochloride 
• 84669-47-6 7-Methyl-4-phenoxymethyl-chromen-2-one 
• 108154-47-8 4-(5-Chloro-benzofuran-2-yl)-7-methyl-chromen-2-one 
• 79344-57-3 4-Anilinomethyl-7-methylcoumarin 
• 84669-51-2 7-methyl-4-[4'-chlorophenoxymethyl]-coumarin 
• 84669-49-8 7-Methyl-4-o-tolyloxymethyl-chromen-2-one 
• 84669-72-7 7-Methyl-4-phenylsulfanylmethyl-chromen-2-one 
• 126933-74-2 2-(7-Methyl-2-oxo-2H-chromen-4-ylmethyl)-3-oxo-N-phenyl-butyramide 
• 79344-55-1 4-[(4-Methoxy-phenylamino)-methyl]-7-methyl-chromen-2-one 
• 108154-44-5 4-Benzofuran-2-yl-7-methyl-chromen-2-one 
• 79344-54-0 7-methyl-4-[4'-chloroanilinomethyl]-coumarin 
• 79344-56-2 7-Methyl-4-(p-tolylamino-methyl)-chromen-2-one 

Relevant articles and documents

Reaction of 4-Haloacetoacetate with Phenols in the Presence of Aluminium Chloride

Reaction of ethyl 4-bromoacetoacetate (1) with phenol in the presence of aluminium chloride gave ethyl 4-bromo-3-hydroxy-3-(2-hydroxyphenyl)butyrate (3a), which can be regarded as an intermediate of the Pechmann reaction.Similar reaction of ethyl 4-chloroacetoacetate (7) with phenol in the presence of aluminium chloride gave the 4-chloro derivative 8a.Compound 3a was treated with either hydrogen chloride in ethanol or triethylamine followed by treatment with p-toluenesulfonic acid to give 4-bromomethylcoumarin (4a) or ethyl 3-benzofuranacetate (6a), respectively.Similarly, reactions of phenol derivatives 2 with 1 gave the corresponding 3-hydroxybutyrates 3, which were transformed to the coumarins 4 and the 3-benzofuranacetates 6.