41359-25-5

Basic information

• Product Name: Imidazolidine, 1,3-dihydroxy-2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-
• CAS NO: 41359-25-5
• Molecular Formula: C14H22N2O3
• Molecular Weight: 266.34
• Mol File: 41359-25-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Imidazolidine, 1,3-dihydroxy-2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazolidine, 1,3-dihydroxy-2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-(41359-25-5)
• EPA Substance Registry System: Imidazolidine, 1,3-dihydroxy-2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-(41359-25-5)

Safety Data

• Hazardous Substances Data: 41359-25-5(Hazardous Substances Data)

Upstream product

• 3964-18-9 2,3-dimethyl-2,3-dinitrobutane 
• 123-11-5 4-methoxy-benzaldehyde 
• 14384-45-3 N,N'-dihydroxy-2,3-dimethylbutane-2,3-diamine 

Downstream Products

• 117566-76-4 2-methoxyphenyl-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazolyl-1-oxy 3-oxide 
• 735278-99-6 1-(acetyloxy)-2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole 
• 735279-06-8 1,4,4,5,5-pentamethyl-2-(4-methoxyphenyl)-4,5-dihydro-1H-imidazole 3-oxide 
• 735278-76-9 2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-1-ol 
• 191285-93-5 2-(4-methoxyphenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-1-oxyl 

Relevant articles and documents

Laccases for bio-bleaching

Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins and other phenolic and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

1,3-Alternate calix[4]arene nitronyl nitroxide tetraradical and diradical: synthesis, X-ray crystallography, paramagnetic NMR spectroscopy, EPR spectroscopy, and magnetic studies

Calix[4]arenes constrained to 1,3-alternate conformation and functionalized at the upper rim with four and two nitronyl nitroxides have been synthesized, and characterized by X-ray crystallography, magnetic resonance (EPR and 1H NMR) spectroscopy, and magnetic studies. Such calix[4]arene tetraradicals and diradicals provide scaffolds for through-bond and through-space intramolecular exchange couplings.

Novel 2-substituted nitronyl nitroxides as free radical scavengers: Synthesis, biological evaluation and structure-activity relationship

To develop more potent small molecules with enhanced free radical scavenger properties, we designed and synthesized a series of nitronyl nitroxide derivatives 4a-h. A lead compound 4f was discovered based on Ach-induced vascorelaxation assay. Further chemical modification based on this scaffold provided a new series of 2-substituted phenylnitronyl nitroxide derivatives 6a-s. The newly synthesized compounds 6a-s possess improved radical scavenger's activity based on PC12 cell survival assay. Compounds 6g,n,o, and s are some of the most potent compounds in terms of NO, H2O2, and OH scavenging ability. 2-Substitued phenylnitronyl nitroxides had a higher radical scavenging activity with the electron-donating group (EDG). In contrast, the introduction of electron-withdrawing group (EWG) to the aromatic ring led to a dramatic decrease in its radical scavenging activity. These results suggest that the electron-donating group (EDG) of the aromatic ring may be an important factor influencing the radical scavenging behavior of these compounds, and the potency of free radical scavenging activity largely depended on the position and electronic properties of the phenyl ring substituents. The enhanced radical scavenging capacities of the novel 2-substituted nitronyl nitroxides may be potential drug leads against the deleterious action of ROS (reactive oxygen species)/RNS (reactive nitrogen species).