41360-32-1

Basic information

• Product Name: alpha-Sulfophenylacetic acid
• Synonyms: Alpha-Phenylsulfoacetic Acid;ALPHA SULFOPHENYLACETIC ACID;2-Sulfophenylacetic Acid;A-SULFOPHENYLACETIC ACID;α-Sulfophenylacetic acid;D-SFA 15% aqueouse solution;2-Phenyl-2-sulfoacetic acid;Benzeneacetic acid, a-sulfo-
• CAS NO: 41360-32-1
• Molecular Formula: C₈H₈O₅S
• Molecular Weight: 216.21
• EINECS: 1312995-182-4
• Product Categories: Pharmaceutical Intermediates;Intermediates
• Mol File: 41360-32-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 225 °C
• Appearance: /
• Density: 1.587 g/cm³
• Refractive Index: 1.622
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.12±0.50(Predicted)
• CAS DataBase Reference: alpha-Sulfophenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-Sulfophenylacetic acid(41360-32-1)
• EPA Substance Registry System: alpha-Sulfophenylacetic acid(41360-32-1)

Safety Data

• Hazardous Substances Data: 41360-32-1(Hazardous Substances Data)

Usage

Uses

Alpha-sulfophenylacetic acid

InChI:InChI=1/C8H8O5S/c9-8(10)7(14(11,12)13)6-4-2-1-3-5-6/h1-5,7H,(H,9,10)(H,11,12,13)

Upstream product

• 103-82-2 phenylacetic acid 
• 107-06-2 1,2-dichloro-ethane 
• 7664-93-9 sulfuric acid 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 

Downstream Products

• 39925-35-4 2-sulfo-2-phenylacetyl chloride 
• 39925-38-7 2-phenyl-2-sulfoacetic acid 
• 28002-18-8 (2S,5R,6R)-3,3-dimethyl-6-(2-phenyl-2-sulfoacetylamino)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid disodium salt 
• 858004-74-7 (+/-)-phenyl-phenylcarbamoyl-methanesulfonic acid ; (+/-)-α-sulfo-phenylacetic acid anilide 

Relevant articles and documents

To facilitate the industrial production of synthesis method of sulbenicillin sodium (by machine translation)

The invention discloses a method of easy industrial production sulbenicillin sodium synthetic method, comprises the following steps: (1) sulfonation reaction; (2) alkalization reaction; (3) ion exchange; (4) chloro acylation reaction; (5) extracting sulphur benzene acetyl chloride; (6) preparation of (-) - α - D - sulbenicillin; (7) the preparation of (-) - α - D - sulbenicillin sodium. The invention relates to a convenient industrial production of synthetic method of sulbenicillin sodium, through reasonable synthetic route design, simplifies the sulphur benzene acetic acid disodium salt of the tedious operation, improves the yield; direct the synthetic process for preparing optically pure (-) - α - D - of sulbenicillin, saves the cost, more favorable to the industrialized production, market prospect. (by machine translation)

Cis-4-oxoazetidine intermediates and methods of preparing them

The stereospecific cycloaddition of nitrogen containing acetic acid halides or anhydrides with Schiff bases having a carbalkoxy group substituted on the methine carbon atom offers new intermediates and methods for preparing synthetic cephalosporin congeners having antibacterial activity.