41545-56-6

Basic information

• Product Name: 1,2,3,4,6-PENTA-O-BENZOYL-BETA-D-GALACTOSE
• Synonyms: BETA-D-GALACTOSE-PENTABENZOATE;1,2,3,4,6-PENTA-O-BENZOYL-BETA-D-GALACTOSE;beta-D-Galactose-pentabenzoat;1,2,3,4,6-Penta-O-benzoyl-beta-D-galactopyranose;1,2,3,4,6-Penta-O-benzoyl-b-D-galactose;Penta-O-benzoyl-beta-D-galactopyranose;beta-D-Galactopyranose pentabenzoate
• CAS NO: 41545-56-6
• Molecular Formula: C₄₁H₃₂O₁₁
• Molecular Weight: 700.69
• Mol File: 41545-56-6.mol
• Article Data: 79

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3,4,6-PENTA-O-BENZOYL-BETA-D-GALACTOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4,6-PENTA-O-BENZOYL-BETA-D-GALACTOSE(41545-56-6)
• EPA Substance Registry System: 1,2,3,4,6-PENTA-O-BENZOYL-BETA-D-GALACTOSE(41545-56-6)

Safety Data

• Hazardous Substances Data: 41545-56-6(Hazardous Substances Data)

Usage

Type of compound

Chemical compound

Derivative of

Beta-D-galactose

Number of benzoyl groups

Five

Positions of benzoyl groups

1, 2, 3, 4, and 6

Applications

Organic synthesis, pharmaceuticals, and agrochemicals

Building block

Versatile for the synthesis of complex molecules

Field of potential applications

Glycobiology

Solubility

Useful in research and industrial applications

Stability

Useful in research and industrial applications

Upstream product

• 530-26-7 D-Mannose 
• 98-88-4 benzoyl chloride 
• 2280-44-6 D-Glucose 
• 93-97-0 benzoic acid anhydride 
• 3458-28-4 D-Mannose 
• 10257-28-0 D-Galactose 
• 59-23-4 D-Galactose 
• 105376-04-3 ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-galactopyranoside 
• 65-85-0 benzoic acid 
• 627466-64-2 2,3,4,6-tetra-O-benzoyl-D-glucopyranose 
• 492-62-6 alpha-D-glucopyranose 
• 50-99-7 D-glucose 
• 3646-73-9 α-D-galactopyranose 
• 69534-63-0 1,2,3,4,6-penta-O-benzoyl-5-C-bromo-β-D-glucopyranose 

Downstream Products

• 6605-40-9 methyl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 113544-59-5 O²,O³,O⁴,O⁶-Tetrabenzoyl-D-mannose 
• 2592-58-7 1,2,3,4,6-penta-O-benzoyl-α-D-mannopyranoside 
• 64768-20-3 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 14726-07-9 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl iodide 
• 865470-38-8 3-butenyl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 125367-09-1 n-pent-4-enyl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 
• 6605-40-9 methyl 2,3,4,6-tetra-O-benzyl-β-D-glucopyranoside 
• 64768-20-3 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranose 
• 149707-76-6 O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl) trichloroacetimidate 
• 105376-04-3 ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside 
• 245368-66-5 ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-α-D-glucopyranoside 
• 149707-75-5 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate 

Relevant articles and documents

Synthesis, molecular docking analysis and biological evaluations of saccharide-modified thiadiazole sulfonamide derivatives

A series of saccharide-modified thiadiazole sulfonamide derivatives has been designed and synthesized by the “tail approach” and evaluated for inhibitory activity against carbonic anhydrases II, IX, and XII. Most of the compounds showed high topological polar surface area (TPSA) values and excellent enzyme inhibitory activity. The impacts of some compounds on the viability of HT-29, MDA-MB-231, and MG-63 human cancer cell lines were examined under both normoxic and hypoxic conditions, and they showed certain inhibitory effects on cell viability. Moreover, it was found that the series of compounds had the ability to raise the pH of the tumor cell microenvironment. All the results proved that saccharide-modified thiadiazole sulfonamides have important research prospects for the development of CA IX inhibitors.

N-aryl sulfanilamide-N-beta-D-glucopyranose diamide compound and application thereof

The invention belongs to the technical field of medicines, and relates to a preparation method and medical application of an N1-aryl sulfanilamide-N4-beta-D-glucopyranose diamide compound. The compound is shown in a general formula (I), substituent groups are described in the specification, and the compound shown in the general formula (I) and an optical active body, a diastereoisomer and a pharmaceutically acceptable salt thereof are applied to preparation of anti-tumor drugs. Based on pharmacophore characteristics and subcellular localization of CA IX and XII, a selective CA IX and XII inhibitor is designed and synthesized, polyhydroxy high-polarity glucose is selected as a tail end, a classical pharmacophore aryl sulfanilamide fragment of a targeted CAs active center is introduced through a flexible aliphatic chain and a rigid aromatic structure, the overall structure can selectively inhibit catalytic activity of extracellular CA IX and XII, an anti-tumor effect is achieved, and therefore, the compound has a good application prospect.

Preparation method of glycyrrhetinic acid glucoside and application of glycyrrhetinic acid glucoside in sweetening agents

The invention relates to a synthetic route of glycyrrhetinic acid glucoside and application of glycyrrhetinic acid glucoside in sweetening agents, and belongs to the field of synthesis of novel sweetening agents. The novel sweetening agent with higher swe