417725-91-8 Usage
General Description
1-Isoquinolineacetic acid, 1,2,3,4-tetrahydro-6,7-dimethoxy-, methyl ester, (1S)-, also known as (S)-Tetrahydropapaverine, is a chemical compound that belongs to the isoquinoline alkaloid class. It is a methyl ester of 1-isoquinolineacetic acid and is commonly found in various plants. It is known for its potential medicinal properties, including its use as a smooth muscle relaxant and vasodilator. Its chemical structure and properties make it a promising candidate for research in the development of new drugs for cardiovascular diseases and other conditions. Additionally, it has been studied for its potential in the treatment of addiction and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 417725-91-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,7,7,2 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 417725-91:
(8*4)+(7*1)+(6*7)+(5*7)+(4*2)+(3*5)+(2*9)+(1*1)=158
158 % 10 = 8
So 417725-91-8 is a valid CAS Registry Number.
417725-91-8Relevant articles and documents
A study of Aryl radical cyclization in enaminone esters
Navarro-Vazquez, Armando,Garcia, Alberto,Dominguez, Domingo
, p. 3213 - 3220 (2007/10/03)
Aryl radical cyclization in N-phenyl, N-benzyl, and N-phenethyl enaminone esters 1a-f was studied. N-Benzyl and N-phenethyl enaminones afforded 5-exo and 6-exo cyclization products, respectively, but radical cyclization did not occur in N-phenyl enaminones. The rate constants for the 5-exo and 6-exo cyclization processes in secondary enaminones were estimated as being on the order of 107 s-1 at 353 K; since DNMR experiments showed the rate constant for rotation around the enaminone C3-N bond to be on the order of 104 s-1 at this temperature, the initial enaminone configuration is maintained throughout the cyclization process. PM3 calculations suggested that the nonoccurrence of endo and 4-exo cyclizations is due to the corresponding transition structures involving significant distortion of the conjugated enaminone system.
