41819-75-4

Basic information

• Product Name: 4-ETHYL-2-PYRROLIDINONE
• Synonyms: 4-ETHYL-2-PYRROLIDINONE;4-ethyl-2-pyrrolidinone(SALTDATA: FREE);4-Ethylpyrrolidin-2-one
• CAS NO: 41819-75-4
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.16
• Mol File: 41819-75-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 250.9°C at 760 mmHg
• Flash Point: 136.5°C
• Appearance: /
• Density: 0.952g/cm³
• Vapor Pressure: 0.0211mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: 4-ETHYL-2-PYRROLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYL-2-PYRROLIDINONE(41819-75-4)
• EPA Substance Registry System: 4-ETHYL-2-PYRROLIDINONE(41819-75-4)

Safety Data

• Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 41819-75-4(Hazardous Substances Data)

Usage

General Description

4-Ethyl-2-pyrrolidinone is a chemical compound with the molecular formula C6H11NO. It is a colorless to pale yellow liquid with a mild odor, and is commonly used as a solvent in various industrial applications. 4-Ethyl-2-pyrrolidinone is known for its high solvency and low volatility, making it useful for dissolving a wide range of substances, including polymers, resins, and dyes. It is also used as a reaction medium for chemical processes, and as a component in various cleaning and coating formulations. Additionally, it is a precursor in the production of other chemicals, such as pharmaceuticals and agrochemicals. Due to its versatility and effectiveness as a solvent, 4-ethyl-2-pyrrolidinone is widely utilized in industries such as pharmaceuticals, textiles, and electronics.

InChI:InChI=1/C6H11NO/c1-2-5-3-6(8)7-4-5/h5H,2-4H2,1H3,(H,7,8)

Upstream product

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Relevant articles and documents

Evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2-imines as inhibitors of nitric oxide synthase

Syntheses and evaluation of pyrrolidin-2-imines and 1,3-thiazolidin-2- imines as inhibitors of nitric oxide synthase (NOS) are discussed. An extensive SAR was established for pyrrolidin-2-imines class of compounds. The amidines came out as the most potent inhibitors in addition to displaying selectivity.

Preparation of lactams from aliphatic α, ω-dinitriles

A process for the preparation of five-membered or six-membered ring lactams from aliphatic α,ω-dinitriles has been developed. In the process an aliphatic α,ω-dinitrile is first converted to an ammonium salt of an ω-nitrile-carboxylic acid in aqueous solution using a catalyst having an aliphatic nitrilase (EC 3.5.5.7) activity, or a combination of nitrile hydratase (EC 4.2.1.84) and arnidase (EC 3.5.1.4) activities. The ammonium salt of the ω-nitrilecarboxylic acid is then converted directly to the corresponding lactam by hydrogenation in aqueous solution, without isolation of the intermediate ω-nitrilecarboxylic acid or ω-aminocarboxylic acid. When the aliphatic α,ω-dinitrile is also unsymmetrically substituted at the α-carbon atom, the nitrilase produces the ω-nitrilecarboxylic acid ammonium salt resulting from hydrolysis of the ω-nitrile group with greater than 98% regioselectivity, thereby producing only one of the two possible lactam products during the subsequent hydrogenation. A heat-treatment process to select for desirable regioselective nitrilase or nitrile hydratase activities while destroying undesirable activities is also provided.

2-Iminopyrrolidines as potent and selective inhibitors of human inducible nitric oxide synthase

A series of substituted 2-iminopyrrolidines has been prepared and shown to be potent and selective inhibitors of the human inducible nitric oxide synthase (hiNOS) isoform versus the human endothelial nitric oxide synthase (heNOS) and the human neuronal ni