41826-92-0

Basic information

• Product Name: Trepibutone
• Synonyms: 2,4,5-triethoxy-gamma-oxobenzenebutanoicacid;3-(2,4,5-triethoxybenzoyl)-propionicaci;3-(2,4,5-triethoxybenzoyl)propionicacid;aa149;colibil;supacal;TREPIBUTONE;4-Oxo-4-(2,4,5-triethoxyphenyl)butanoic acid
• CAS NO: 41826-92-0
• Molecular Formula: C₁₆H₂₂O₆
• Molecular Weight: 310.34
• Mol File: 41826-92-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 150-151°
• Boiling Point: 370.51°C (rough estimate)
• Flash Point: 179.9 °C
• Appearance: /
• Density: 1.1625 (rough estimate)
• Vapor Pressure: 9.27E-11mmHg at 25°C
• Refractive Index: 1.4600 (estimate)
• PKA: 4.40±0.17(Predicted)
• CAS DataBase Reference: Trepibutone(CAS DataBase Reference)
• NIST Chemistry Reference: Trepibutone(41826-92-0)
• EPA Substance Registry System: Trepibutone(41826-92-0)

Safety Data

• Hazardous Substances Data: 41826-92-0(Hazardous Substances Data)

Usage

Originator

Supacal,Takeda,Japan,1981

Manufacturing Process

To a mixture of 7.5 parts by weight of 1,2,4-triethoxybenzene, 40 parts by volume of tetrachloroethane and 7.5 parts by weight of succinic anhydride are added 23 parts by weight of anhydrous aluminum chloride. The mixture is stirred for 1 hour at 25°C and for another 2 hours at 60°C. After addition of 50 parts by weight of ice and 50 parts by volume of concentrated hydrochloric acid, the reaction mixture is subjected to steam distillation. After cooling crystals separated from the remaining liquid are collected by filtration and recrystallized from aqueous ethanol, whereby 2.5 parts by weight of 3-(2',4',5'-triethoxybenzoyl)-propionic acid are obtained as colorless needles, melting point 150°C to 151°C.

Therapeutic Function

Choleretic

InChI:InChI=1/C16H22O6/c1-4-20-13-10-15(22-6-3)14(21-5-2)9-11(13)12(17)7-8-16(18)19/h9-10H,4-8H2,1-3H3,(H,18,19)

Upstream product

• 3878-55-5 methyl hydrogen succinate 
• 41827-15-0 1,2,4-triethoxy-benzene 

Downstream Products

• 63213-45-6 3-(2'-hydroxy-4',5'-diethoxybenzoyl)propionic acid 
• 63213-35-4 4-(2,4,5-Triethoxybenzoyl)-buttersaeure 
• 63213-27-4 4-[4-oxo-4-(2,4,5-triethoxy-phenyl)-butyryl]-morpholine 

Relevant articles and documents

Therefore, performance and manufacturing method thereof having a cement additive

The present invention provides a cement admixture that comprises at least one of a carboxylic acid based copolymer comprising a reactive surfactant as a monomer or a copolymer salt obtained by neutralizing the copolymer with an alkaline substance, a method for preparing the same, and a cement composition comprising the same. The cement admixture of the present invention increases composition fluidity even at a high water-reducing formulation by improving dispersibility of cement particles, prevents a decrease of fluidity as the function of time, and offers good workability by supplying an adequate amount of air flow continuously.

3-(Trisubstituted benzoyl)-propionic acid

The present invention relates to a compound of the formula: SPC1 Wherein R1 is an alkyl group of 1 to 4 carbons, an alkoxy group of 1 to 4 carbons or hydroxyl, and R2 and R3 are either the same or different and may be an a