41860-63-3

Basic information

• Product Name: 2,4,6-TRIFLUOROIODOBENZENE
• Synonyms: 1,2,4-trifluoro-5-iodobenzene;1,3,5-Trifluoro-2-iodobenzene
• CAS NO: 41860-63-3
• Molecular Formula: C₆H₂F₃I
• Molecular Weight: 257.98
• Product Categories: Miscellaneous
• Mol File: 41860-63-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 28-29℃
• Boiling Point: 171℃
• Flash Point: 63℃
• Appearance: /
• Density: 2.078
• Vapor Pressure: 1.26mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2,4,6-TRIFLUOROIODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIFLUOROIODOBENZENE(41860-63-3)
• EPA Substance Registry System: 2,4,6-TRIFLUOROIODOBENZENE(41860-63-3)

Safety Data

• Hazardous Substances Data: 41860-63-3(Hazardous Substances Data)

Usage

General Description

2,4,6-Trifluoroiodobenzene is a chemical compound with the molecular formula C6H2F3I. It is a derivative of benzene with three fluorine atoms and one iodine atom attached to the benzene ring. 2,4,6-Trifluoroiodobenzene is primarily used in organic synthesis as a building block for various chemical reactions. 2,4,6-Trifluoroiodobenzene is an important intermediate in the production of agrochemicals, pharmaceuticals, and materials. It is also used in the development of new materials for electronic and optical applications due to its unique properties. Additionally, this compound has potential applications in the field of medicinal chemistry as a starting material for the synthesis of biologically active compounds.

InChI:InChI=1/C6H2F3I/c7-3-1-5(9)6(10)2-4(3)8/h1-2H

Upstream product

• 372-38-3 1,3,5-trifluorobenzene 

Downstream Products

• 84322-55-4 1,3,5-trifluoro-2,4-diiodobenzene 

Relevant articles and documents

Utilising Sodium-Mediated Ferration for Regioselective Functionalisation of Fluoroarenes via C?H and C?F Bond Activations

Pairing iron bis(amide) Fe(HMDS)2 with Na(HMDS) to form new sodium ferrate base [(dioxane)0.5?NaFe(HMDS)3] (1) enables regioselective mono and di-ferration (via direct Fe?H exchange) of a wide range of fluoroaromatic substrates under mild reaction conditions. Trapping of several ferrated intermediates has provided key insight into how synchronised Na/Fe cooperation operates in these transformations. Furthermore, using excess 1 at 80 °C switches on a remarkable cascade process inducing the collective twofold C?H/threefold C?F bond activations, where each C?H bond is transformed to a C?Fe bond whereas each C?F bond is transformed into a C?N bond.

A simple base-mediated halogenation of acidic sp2 C-H bonds under noncryogenic conditions

(Chemical Equation Presented) A new method has been developed for in situ halogenation of acidic sp2 carbon-hydrogen bonds in heterocycles and electron-deficient arenes. Either selective monohalogenation or one-step exhaustive polyhalogenation is possible for substrates possessing several C-H bonds that are flanked by electron-withdrawing groups. For the most acidic arenes, such as pentafluorobenzene, K3PO4 base can be employed instead of BuLi for metalation/halogenation sequences.

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.