41890-92-0

Basic information

• Product Name: 7-methoxy-3,7-dimethyloctan-2-ol
• Synonyms: 7-methoxy-3,7-dimethyloctan-2-ol;METHOXYTRIMETHYLHEPTANOL;3,7-Dimethyl-7-methoxyoctan-2-ol;2-Octanol, 7-methoxy-3,7-dimethyl-;3,7-Dimethyl-7-methoxy-2-octanol;7-Methoxy-3,7-dimethyl-2-octanol
• CAS NO: 41890-92-0
• Molecular Formula: C₁₁H₂₄O₂
• Molecular Weight: 188.30706
• EINECS: 255-574-7
• Mol File: 41890-92-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 263.33°C (rough estimate)
• Flash Point: 65.1°C
• Appearance: /
• Density: 0.9217 (rough estimate)
• Vapor Pressure: 0.0125mmHg at 25°C
• Refractive Index: 1.4260 (estimate)
• PKA: 15.10±0.20(Predicted)
• CAS DataBase Reference: 7-methoxy-3,7-dimethyloctan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-3,7-dimethyloctan-2-ol(41890-92-0)
• EPA Substance Registry System: 7-methoxy-3,7-dimethyloctan-2-ol(41890-92-0)

Safety Data

• Hazardous Substances Data: 41890-92-0(Hazardous Substances Data)

Usage

Chemical Properties

7-Methoxy-3,7-dimethyl-2-octanol is a clear, almost colorless liquid with sandalwood odor, which has a floral, woody note. It is not known to have been found in nature. 7-Methoxy-3,7-dimethyl-2-octanol is prepared by hydrochlorination of dihydromyrcene, methoxylation of the resulting 2-chloro-2,6-dimethyl-7-octene, and epoxidation. The alcohol is obtained by hydrogenation of the epoxide in the presence of Raney nickel and triethylamine. It is used in perfumery as a top note in high-quality sandalwood compositions for cosmetics, toiletries, and soaps.

Trade name

Osyrol (Innospec).

InChI:InChI=1/C11H24O2/c1-9(10(2)12)7-6-8-11(3,4)13-5/h9-10,12H,6-8H2,1-5H3

Upstream product

• 40454-19-1 7,8-epoxy-2-methoxy-2,6-dimethyloctane 
• 2436-90-0 (+)-β-citronellene 
• 53767-86-5 7-methoxy-3,7-dimethyloct-1-ene 
• 53767-87-6 7-methoxy-3,7-dimethyl-octan-2-one 

Relevant articles and documents

Selective palladium nanoparticles-catalyzed hydrogenolysis of industrially targeted epoxides in water

Palladium nanoparticles, with core sizes of ca. 2.5 nm, were easily synthesized by chemical reduction of Na2PdCl4 in the presence of hydroxyethylammonium salts and proved to be efficient for the selective hydrogenolysis of various aromatic, alkylphenyl, aliphatic epoxides in water as green solvent. Capping agents of the metal species were screened to define the most suitable micellar nanoreactors on two target substrates of industrial interest, epoxystyrene and 7,8-epoxy-2-methoxy-2,6-dimethyloctane. In our conditions, the hydrogenolysis of epoxystyrene proved to be pH-dependent, producing either the diol under acidic conditions, or the sweet-smelling 2-phenylethanol in the presence of a base. Promisingly, 7,8-epoxy-2-methoxy-2,6-dimethyloctane was completely and selectively hydrogenated into Florsantol, a sandalwood odorant at a multigram scale (40 g and up to 175g). A general mechanism for the palladium nanoparticles-catalyzed hydrogenolysis of terminal epoxides was proposed according to steric and electronic properties and finely corroborated with deuterium labelling experiments.

Compounds having protected hydroxy groups

The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.

Ketone precursors for organoleptic compounds

The invention discloses ketones of formula I: wherein, Y is an optionally substituted alkyl, cycloalkyl, or cycloalkylalkyl, wherein each alkyl group is straight or branched and each alkyl and cycloalkyl group is saturated or unsaturated; R1is hydrogen or a C1-6alkyl group that is substituted, saturated or unsaturated, straight or branched; A is a chromophoric substituted aromatic ring or ring system; n is an integer; and with the proviso that formula I is not 2-ethoxy-1-phenyl-ethanone. These compositions are useful for the delivery of organoleptic compounds, especially of flavors, fragrances, masking agents and antimicrobial compounds.